051
Secondary isotope effects on the deslipping reaction of rotaxanes: High-precision measurement of steric size

T. Felder, C. A. Schalley – 2003

A supramolecular measuring instrument for determining steric size: The deslipping reaction of the rotaxane shown with deuterated stopper groups senses the smaller steric size of the deuterium atom and proceeds with a 10?% higher reaction rate than the reaction of the unlabeled rotaxane. This result sheds new light from a supramolecular point of view on the classical problem of determining steric demand.

Title
051
Secondary isotope effects on the deslipping reaction of rotaxanes: High-precision measurement of steric size
Author
T. Felder, C. A. Schalley
Date
2003-05-23
Identifier
DOI 10.1002/anie.200350903; 10.1002/ange.200350903
Citation
Angew. Chem. Int. Ed. 2003, 42, 2258-2260; Angew. Chem. 2003, 115, 2360-2363
Type
Text