164
Phenanthroline- and Terpyridine-Substituted Tetralactam Macrocycles: A Facile Route to Rigid Di- and Trivalent Receptors and Interlocked Molecules

E. V. Dzyuba, B. Baytekin, D. Sattler, C. A. Schalley – 2011

Bromo-substituted Hunter/Vögtle-type tetralactam macrocycles (TLMs) represent key intermediates for the attachment of terpyridyl and phenanthroline metal binding sites through cross-coupling reactions. From these monovalent precursors, metal complexes can easily be obtained that present the macrocycles in a multivalent fashion. Depending on the nature of the metal ion, the properties of the complexes can be tuned with respect to valency (e.g., phen-TLM + CuI: divalent, phen-TLM + FeII: trivalent) and lability against TLM ligand exchange (e.g., CuI: slow, but reversible exchange, RuIICl2: kinetically inert).

Title
164
Phenanthroline- and Terpyridine-Substituted Tetralactam Macrocycles: A Facile Route to Rigid Di- and Trivalent Receptors and Interlocked Molecules
Author
E. V. Dzyuba, B. Baytekin, D. Sattler, C. A. Schalley
Date
2011-12-28
Identifier
DOI 10.1002/ejoc.201101231
Source(s)
Citation
Eur. J. Org. Chem. 2012, 1171-1178