Our research aims to develop methods to generate tailor-made polymers with defined charged sequences. We want to combine techniques from polymer chemistry, simple and efficient organochemical reactions, and inspirations from peptide chemistry to synthesize products that can serve as peptide mimetics or complexation agents for biomolecules in vivo. At the moment, we focus on monodisperse, amine-based cations with different architectures that can mimic host defense peptides (HDPs) or other biomedically relevant peptide structures.