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Paper on Pneumolysin inhibitors published in Nature Communications

News from May 27, 2024

Based on virtual screening and docking experiments by our molecuar design lab, a new small molecule inhibitor for blocking pnemolysin, the Streptococcus pneumoniae toxin could be identified, derivatized and biologically characterized by the group of Jörg Rademann at our institute.

Link to the paper: Targeted small molecule inhibitors blocking the cytolytic effects of pneumolysin and homologous toxins | Nature Communications

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