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Partners

I. RESEARCH

I.1 Research Consortia

I.1.1 Structured PhD program “PharMetrX” (since 2008): www.PharMetrX.de/Chairs:

  • Prof. Dr. Charlotte Kloft, Dept. Clinical Pharmacy & Biochemistry, Institute of Pharmacy, Freie Universität Berlin, DE
  • Prof. Dr. Wilhelm Huisinga, Institut für Mathematik, Universität Potsdam, DE

Coordinator: Cornelia Böhnstedt: contact@PharMetrX.de

I.1.2 EU project “FAIR” (since 2020):
https://fair-flagellin.eu/

Work Package Leader and member of Steering Committee:

  • Prof. Dr. Charlotte Kloft, Dept. Clinical Pharmacy & Biochemistry, Institute of Pharmacy, Freie Universität Berlin, DE

Work Package co-responsible

  • Dr. ir. Robin Michelet, Dept. Clinical Pharmacy & Biochemistry, Institute of Pharmacy, Freie Universität Berlin, DE
  • Dr. Linda Aulin, Dept. Clinical Pharmacy & Biochemistry, Institute of Pharmacy, Freie Universität Berlin, DE

Collaboration partners:

  • Institut National de la Sante et de la Recherche Medicale (INSERM), FRA(coordinator)
  • Academisch Medisch Centrum Bij de Universiteit Van Amsterdam, NL
  • Aerogen Ltd, IRL
  • Centre Hospitalier Regional Universitaire de Tours, FRA
  • Epithelix Sarl, CH
  • European Respiratory Society, CH
  • Inserm Transfert SA, FRA
  • Statens Serum Institut, DK
  • Universite de Lille, FRA
  • University of Southampton, UK

I.1.3 “ON TARGET” (since 2021): www.bcp.fu-berlin.de/pharmazie/faecher/klinische_pharmazie/arbeitsgruppe_kloft/on-target-studie/index.html

Core consortium team

  • Prof. Dr. Charlotte Kloft, Dept. Clinical Pharmacy & Biochemistry, Institute of Pharmacy, Freie Universität Berlin, DE (Team Lead)
  • Prof. Ulrich Jaehde, Dept. Clinical Pharmacy, Institute of Pharmacy, University of Bonn, DE
  • Prof. Oliver Scherf-Clavel, Dept. Chemistry and Pharmacy, Ludwig-Maximilians-Universität München, DE
  • Prof. Georg Hempel, Dept. Pharmaceutical and Medical Chemistry, Clinical Pharmacy, University of Münster, DE

I.1.4 “GlobalResist” (since 2022): www.berlin-university-alliance.de/en/commitments/grand-challenge-initiatives/global-health/expl-projects-gh/globalresist/index.html

Collaboration partners:

  • Prof. Dr. Jens Rolff, Institute of Biology, Freie Universität Berlin, DE (coordinator)
  • Prof. Dr. Sabine Ammon, Institute of Philosophy, History of Literature, and Technology, Technische Universität Berlin, DE
  • PD Dr. Ulrich Kertzscher, Experimental Fluid Mechanics, Charité – Universitätsmedizin Berlin, DE
  • PD Dr. Rasmus Leistner, Dept. Gastroenterology, Infectious Diseases and Rheumatology, Charité – Universitätsmedizin Berlin, DE
  • Prof. Dr. Annette Moter, Institute of Microbiology, Infectious Diseases and Immunology, Biofilmcenter, Charité – Universitätsmedizin Berlin, DE
  • Prof. Dr. Dirk Oberschmidt, Institute of Machine Tools and Factory Management, Technische Universität Berlin, DE


I.2 Research Pillar: Pharmacometrics and Clinical Trials

I.2.1 TIAS study collaboration project (since 2019):

Collaboration partners:

  • Dr. Miriam Songa Stegemann, Dr. Frieder Pfäfflin, Dr. Ulrike Trost, Antimicrobial Stewardship & Dept. Infectious Diseases and Respiratory Medicine, Charité – Universitätsmedizin Berlin, DE
  • Peggy Kießling, Labor Berlin-Charité Vivantes GmbH, Berlin, DE
  • Anja Theloe, Pharmacy Dept., Charité – Universitätsmedizin Berlin, DE

I.2.2 Optimisation of antiinfective therapies (since 2015):

Collaboration partners:

  • PD Dr. Michael Zoller, Dr. Christina Scharf, Dr. Ines Schröder, Dr. Uwe Liebchen, Dept. Anaesthesiology, University Hospital, LMU Munich, DE

I.2.3 Tamoxifen therapy optimisation (since 2021):

Collaboration partners:

  • Prof. Daniel Hertz, Dept. Clinical Pharmacy, University of Michigan, USA, and CEPAM consortium

I.2.4 Survival prediction for CAR-T cell therapy (since 2020):

Collaboration partners:

  • Prof. Annette Künkele, Oncology and Haematology, Charité – Universitätsmedizin Berlin, DE
  • Dr. Philipp Gödel, Oncology and Haematology, University Hospital Köln, DE

I.2.5 Identifying patients at risks of delayed methotrexate elimination using NLME and machine learning approaches (since 2023):

Collaboration partners:

  • Prof. Gerald Illerhaus, Clinic for Haematology, Oncology and Palliative Medicine, Klinikum Stuttgart, DE
  • Dr. Dominik Marschner, Clinic for Internal Medicine I, Uniklinik Freiburg, DE

I.2.6 Investigating the effects of formulation modifications on the pharmacokinetics of pegylated liposomal doxorubicin (since 2023)

Collaboration partners:

  • Prof. Dr. Dr. med. Markus Jörger, Clinic for Medical Oncology and Hematology, Kantonsspital St. Gallen, CH

I.2.7 Optimisation of monoclonal antibodies therapy in inflammatory bowel diseases (since 2012):

Collaboration partners:

  • Dr. Walter Reinisch, Dr. Alexander Eser, Div. Gastroenterology and Hepatology, Dept. of Internal Medicine III, Medical University of Vienna, Vienna, AT
  • Celltrion, Incheon, South Korea
  • Dr. Casper Steenholdt, Prof. Jakob B. Seidelin, Dept. of Gastroenterology, Copenhagen University Hospital-Herlev and Gentofte, Herlev, DK
  • Prof. Mark A. Ainsworth, Camilla Frimor, Dept. of Gastroenterology, Odense University Hospital, Odense, DK
  • Dr. Mette Julsgaard Nielsen, Cæcilie Skejø, Dept. of Hepatology and Gastroenterology, Aarhus University Hospital, Aarhus, DK

I.2.8 Cortisol replacement therapy optimisation in CAH (since 2016):

Collaboration partners:

  • Dr. Richard Ross, Dr. Martin Whitaker, University of Sheffield, UK
  • Dr. Oliver Blankenstein, Dr. Uta Neumann, Paediatric Endocrinology, Charité – Universitätsmedizin Berlin and Labor Berlin Charité Vivantes GmbH, Berlin, DE

I.3 Research Pillar: Bioanalysis & Microdialysis and Cell Cultur

I.3.1 Model-informed pharmacokinetic in vitro metabolism studies (since 2024):

Collaboration partners:

  • Dr. Pieter Annaert, Unit Drug Delivery and Disposition, KU Leuven, Leuven, BE

I.3.2 Optimisation of microdialysis studies including pharmacometrics (since 2023):

Collaboration partners:

  • Dr. Pieter de Cock, Universitair Ziekenhuis Ghent, Dept. of Central Pharmacy
  • Prof. Mathias Devreese, Faculty of Veterinary Medicine Dept. of Pathobiology, Pharmacology and Zoological Medicine
  • Prof. Markus Zeitlinger, Dept. Clinical Pharmacology, Medical University of Vienna, AT
  • Prof. Hermann Wrigge, Dept. Anaesthesiology, Intensive Care and Emergency Medicine, Pain Therapy, Bergmannstrost Hospital Halle, DE
  • Prof. Dr. Philipp Simon, Dept. Anaesthesiology and Intensive Care, Faculty of Medicine, University of Augsburg, DE and Integrated and Treatment Center, Adiposity Diseases, University of Leipzig, DE

I.3.3 Antiinfective combination therapy (since 2023):

Collaboration partners:

  • A./Prof. Cornelia Landersdorfer, Monash Institute of Pharmaceutical Sciences, Monash University, Melbourne, AU

I.3.4 Whole genome sequencing (since 2019):

Collaboration partners:

Dr. Torsten Semmler, Robert-Koch-Institut (RKI), Berlin, D

I.4 Research Pillar: Pharmacometrics and Clinical Trials

Research collaboration partners:

  • Prof. Markus Zeitlinger, Dept. Clinical Pharmacology, Medical University of Vienna, AT
  • Prof. Dr. Markus Joerger, Dept. Internal Medicine, Cantonal Hospital St. Gallen, CH
  • PD Dr. Michael Zoller, Dr. Christina Scharf, Dr. Ines Schröder, Dr. Uwe Liebchen, Dept. Anaesthesiology, University Hospital, LMU Munich, DE
  • Dr. Miriam Songa Stegemann, Dr. Frieder Pfäfflin, Dr. Ulrike Trost, Antimicrobial Stewardship & Dept. Infectious Diseases and Respiratory Medicine, Charité – Universitätsmedizin Berlin, DE
  • Prof. Walter Reinisch, Dr. Alexander Eser, Div. Gastroenterology and Hepatology, Dept. of Internal Medicine III, Medical University of Vienna, AT
  • Dr. Casper Steenholdt, Prof. Jakob B. Seidelin, Dept. Gastroenterology, Copenhagen University Hospital-Herlev and Gentofte, Copenhagen, DK
  • Prof. Mark A. Ainsworth, Dept. Gastroenterology, Odense University Hospital, DK
  • Richard Ross (PhD), Martin Whitaker (PhD), University of Sheffield, UK
  • Dr. Oliver Blankenstein, Dr. Uta Neumann, Paediatric Endocrinology, Charité – Universitätsmedizin Berlin, DE and Labor Berlin Charité Vivantes GmbH, Berlin, DE
  • Prof. Mats O. Karlson, Dr. Elodie L. Plan, Dept. of Pharmacy, Uppsala University, SE
  • Prof. Daniel Hertz, Dept. Clinical Pharmacy, University of Michigan, USA
  • Prof. Ron H.J. Mathijssen, Dr. Stijn L. Koolen, Dept. of Medical Oncology, Erasmus MC Cancer Institute, Rotterdam, NL
  • Prof. Dr. Stefan Holdenrieder, Institute of Laboratory Medicine, Munich Biomarker Research Centre, German Heart Centre of the Free State of Bavaria, Technical University Munich, DE
  • Prof. Cassian Yee,Dept. Melanoma Medical Oncology, Prof. Sattva S. Neelapu Dept. of Lymphoma and Myeloma; both: MD Anderson Cancer Center, University of Texas, Houston, USA
  • PD Dr. Johannes Zander, Institute of Laboratory Medicine, University Hospital, LMU Munich, DE
  • Peggy Kießling, Labor Berlin-Charité Vivantes GmbH, Berlin, DE
  • Anja Theloe, Pharmacy Dept., Charité – Universitätsmedizin Berlin, DE
  • Prof. Peter Hindmarsh, Dept. Paediatric Endocrinology, University College London, UK
  • Prof. Ulrich Jaehde, Dept. Clinical Pharmacy, Institute of Pharmacy, University of Bonn, DE
  • Prof. Thorsten Lehr, Dept. Clinical Pharmacy, Saarland University, Saarbrücken, DE
  • Prof. Gerald Illerhaus, Clinic for Haematology, Oncology and Palliative Medicine, Klinikum Stuttgart, DE
  • Prof. Annette Künkele, Oncology and Haematology, Charité – Universitätsmedizin Berlin, DE
  • Dr. Philipp Gödel, Oncology and Haematology, University Hospital Köln, DE
  • Dr. Lothar Müller, Onkologie UnterEms, Leer, DE
  • Dr. Mette Julsgaard Nielsen, Dept Hepatology and Gastroenterology, Aarhus University Hospital, Aarhus, DK
  • Prof. Martin Schulz, ABDA Bundesvereinigung Deutscher Apothekerverbände, Berlin, DE

I.5 Research Pillar: Bioanalysis & Microdialysis and Cell Culture

Research collaboration partners:

  • Prof. Markus Zeitlinger, Dept. Clinical Pharmacology, Medical University of Vienna, AT
  • Dr. Oliver Blankenstein, Dr. Uta Neumann Paediatric Endocrinology, Charité – Universitätsmedizin Berlin, DE and Labor Berlin Charité Vivantes GmbH, Berlin, DE
  • Prof. Hermann Wrigge, Dept. Anaesthesiology, Intensive Care and Emergency Medicine, Pain Therapy, Bergmannstrost Hospital Halle, DE
  • Prof. Dr. Philipp Simon, Dept. Anaesthesiology and Intensive Care, Faculty of Medicine, University of Augsburg, DE and Integrated and Treatment Center, Adiposity Diseases, University of Leipzig, DE
  • Prof. Dr. Sebastian Günther, Pharmaceutical Biology, Institute of Pharmacy, Universität Greifswald, DE
  • Dr. Torsten Semmler, Robert-Koch-Institut (RKI), Berlin, DE
  • Prof. Jean-Claude Sirard, Institut Pasteur de Lille, Centre d’Infection et d‘Immunité, FRA (coordinator)

I.6 Former research consortia (since 2011)

TAIN project (2014-2018): www.tain-project.org/

ABIMMUNE project (2016-2020): www.jpiamr.eu/projects/abimmune/

Principal investigator and member of Steering Committee:

  • Prof. Dr. Charlotte Kloft, Dept. Clinical Pharmacy & Biochemistry, Institute of Pharmacy, Freie Universität Berlin, DE

Collaboration partners:

  • Prof. Jean-Claude Sirard, Institut Pasteur de Lille, Centre d’Infection et d‘Immunité, FRA (coordinator)
  • Prof. Martin Rumbo, National University of La Plata, Instituto de Estudios Inmunológicos y Fisiopatológicos, AR
  • Prof. Tom van der Poll, Academic Medical Center Amsterdam, NL
  • Prof. Mustapha Si-Tahar, Centre d’Etude des Pathologies Respiratoires, INSERM U1100, Faculté de Médecine Tours, FRA
  • Prof. Sebastian Wicha, Dept. Clinical Pharmacy, Institute of Pharmacy, Hamburg, DE

COMBINATORIALS project (2016-2020): www.jpiamr.eu/projects/combinatorials/

Principal investigator and member of Steering Committee:

  • Prof. Dr. Charlotte Kloft, Dept. Clinical Pharmacy & Biochemistry, Institute of Pharmacy, Freie Universität Berlin, DE

Collaboration partners:

  • Prof. Typas Athanasios, European Molecular Biology Laboratory (EMBL), Genome Biology Unit, DE (coordinator)
  • Prof. Jan-Willem Veening, University of Groningen, Molecular Genetics Department, NL
  • Prof. Frédéric Barras, CNRS, Aix-Marseille Université, Institut de Microbiologie de la Méditerranée, FRA
  • Prof. Birgitta Henriques Normark, Karolinska Institute, Dept. Microbiology, Tumor and Cell Biology, SE
  • Prof. Bernt Eric Uhlin, Umeå University, Dept. Molecular Biology, SE

DDMoRe project (2011-2016): www.imi.europa.eu/projects-results/project-factsheets/ddmore

Work Package Leader and member of Steering Committee:

  • Prof. Dr. Charlotte Kloft, Dept. Clinical Pharmacy & Biochemistry, Institute of Pharmacy, Freie Universität Berlin, DE

26 collaboration partners within EU project of the Innovative Medicines Initiative –Joint Undertaking

1.7 Former research collaboration partners

  • Prof. Alexander Brinkmann, Dr. Otto Frey, Kliniken Landkreis Heidenheim GmbH, Heidenheim an der Brenz, DE
  • Prof. Hartmut Derendorf, Dept. Pharmaceutics, University of Florida, Gainesville, USA
  • Prof. Frieder Kees, Institut für Pharmakologie, & Toxikologie, Universität Regensburg, DE
  • Prof. Joseph L. Kuti, PharmD, Center for Anti-Infective Research and Development, Hartford, USA
  • Prof. Gerd Mikus, Dept. Clinical Pharmacology and Pharmacoepidemiology, University Hospital Heidelberg, DE
  • Prof. Christoph Ritter, Institute of Pharmacy, Clinical Pharmacy, Universität Greifswald, DE
  • Dr. Sebastian Schröpf, Dr. von Haunersches Kinderspital, Ludwig-Maximilians-Universität München, DE
  • Prof. Christoph Stein, Workspace of Experimental Anesthesiology, Charité – Universitätsmedizin Berlin, DE

II. Teaching

II.1 External docents in undergraduate pharmacy curriculum

  • Dr. Jörg Brüggmann, Zentralapotheke Unfallkrankenhaus Berlin, DE
  • Dr. Christiane Eickhoff, ABDA - Bundesvereinigung Deutscher Apothekerverbände, Berlin, DE
  • PD Dr. Andrea Haase, Bundesinstitut für Risikobewertung, Berlin, DE
  • Dr. André Schäftlein, Apotheke der Havelland Kliniken, Nauen, DE
  • Prof. Martin Schulz, ABDA - Bundesvereinigung deutscher Apothekerverbände, Berlin, DE
  • Dr. Ulrich Warnke, Apotheke Ernst von Bergmann Klinikum, Potsdam, DE
  • Prof. Dr. Wolfram Herrmann, Institute of General Practice and Family Medicine, Charité – Universitätsmedizin Berlin, DE
  • Dr. Sabine Gehrke-Beck, Institute of General Practice and Family Medicine, Charité – Universitätsmedizin Berlin, DE
  • Dr. Ronja Behrend, Dean’s Office for Student Affairs, Charité – Universitätsmedizin Berlin, DE
  • Prof. Dr. Harm Peters, Dieter Scheffner Center for Medical Education and Educational Research, Charité – Universitätsmedizin Berlin, DE

II.2 Former external docents in undergraduate pharmacy curriculum

  • Dipl.-Pharm. Annett Sleinitz, Ruppiner Kliniken Apotheke, Neuruppin, DE
  • Prof. Dr. Sebastian Wicha, Clinical Pharmacy, Universität Hamburg, DE
  • Prof. Volker Haucke and coworkers, Leibniz-Institut für Molekulare Pharmakologie, Berlin, DE