PharMetrX I2 module (“Industry internship”) at Boehringer Ingelheim
As part of the structured PhD program PharMetrX, Franziska Kluwe, doctoral student in the area of pharmacometrics, will join the pharmacometrics team at Boehringer Ingelheim Pharma GmbH & Co. KG, Biberach an der Riß/Germany, as an intern from February to April 2019.
For more information about PharMetrX and the I2 module, please visit: https://www.pharmetrx.de/training/curriculum/intership-industry-partners.html
PharMetrX Module Curriculum: A2 module
From 25-29 March 2019, the PharMetrX A2 module “Introduction to physiologically-based pharmacokinetics” will take place at the Universitaet Potsdam. For more detailed information on the module and the structured Graduate Research Training program PharMetrX, please visit our homepage www.PharMetrx.de.
PharMetrX Module Curriculum: Kick-off
From 11 – 15 March 2019, the PharMetrX Module Curriculum for the new PhD student year of our program will start with the A1 module “Introduction to pharmacokinetics and pharmacodynamics” taking place at our Institute. For more detailed information on the module and the structured Graduate Research Training program PharMetrX, please visit our homepage www.PharMetrx.de
Presentations at AMR Conference 2019, Berlin
The Senior Scientist of our working group, Dr. Robin Michelet, will present the results of the joint “COMBINATORIALS” research consortium project at the 12th Conference on Life Sciences on Novel Antimicrobials & AMR Diagnostics in Berlin. The topic of his oral presentation is “Applying the general pharmacodynamic interaction model on high-throughput combinatorial data in order to identify drug combinations that can overcome multi-drug-resistance”.
Oral presentation at Digestive Disease Week 2019
Our work entitled “Infliximab clearance is decreased during 2nd and 3rd trimesters of pregnancy in inflammatory bowel disease” performed in collaboration with Herlev Hospital (Denmark) and Sheba Medical Centre (Israel) has been selected for oral presentation at the Digestive Disease Week in San Diego, CA, USA. The presentation will take place on 18 May 2019 as part of the session “The Pregnant Patient: Therapy and Diagnostics”.
New scientific publication of Department
The manuscript, “High voriconazole target-site exposure after approved sequence dosing due to nonlinear pharmacokinetics assessed by long-term microdialysis” by Kirbs et al. has been published in the Eur. J. Pharm. Sci (doi: 10.1016/j.ejps.2019.02.001). A key component of the analysis was the evaluation of the relationship between CYP2C19 genotype-predicted phenotype and voriconazole clearance.
PBPK workshop using PK-Sim and MoBi
Jointly with SGS Exprimo our Department will organise a 2-day workshop on the use of the open source software PK-Sim and MoBi. The event will take place in the Institute of Pharmacy from 21–22 February 2019. A combination of lectures, demos and hands-on sessions will be used as teaching methods during the workshop featuring examples including predictions of human dose and drug-drug interactions (DDI).
The AK Kloft is glad to welcome a new member
In March 2019, a new doctoral student Alix Demaris will join our Department. Her doctoral thesis project will be in the area of pharmacometrics of monoclonal antibodies.
Scientific workshop with Prof. Meibohm, UTHSC
On 22 January 2019, Prof. Bernd Meibohm from the University of Tennessee Health Science Center, Memphis, TN, USA, will visit our Department again for a scientific workshop. The workshop will comprise of lectures given by Prof. Meibohm and presentations of PhD students. Prof. Meibohm’s research is focused on the investigation of the pharmacokinetics (PK) and pharmacodynamics (PD) of drugs with special emphasis on PK/PD relations of macromolecular drugs.