Naphthocage: A Flexible yet Extremely Strong Binder for Singly Charged Organic Cations
Jia, Fei and Hupatz, Henrik and Yang, Liu-Pan and Schröder, Hendrik V. and Li, Dong-Hao and Xin, Shan and Lentz, Dieter and Witte, Felix and Xie, Xiaojiang and Paulus, Beate and Schalley, Christoph A. and Jiang, Wei – 2019
We report a quite flexible naphthol-based cage (so-called “naphthocage”) which adopts a self-inclusion conformation in its free state and is able to bind singly charged organic cations extremely strongly (Ka > 10e7 M–1). Ion-selective electrodes prepared with this naphthocage show a super-Nernstian response to acetylcholine. In addition, the highly stable complex (10e10 M–1) between ferrocenium and the naphthocage can be switched electrochemically, which lays a basis for its application in stimuli-responsive materials.