635. Development of functional filter materials for virus protective face masks
F. Zabihi, J. Reissner, A. Friese, M. Schulze, C. Nie, P. Nickl, L. Lehmann, P. Siller, C. Melcher, T. Schneiders, T. Gries, U. Rösler, R. Haag – 2023
Wearing face masks during pandemics is an important protective measure against spreading of virus-related infectious diseases. Nevertheless, the risk of indirect transmission of virus by handling masks is one of the earliest concerns. This problem can be minimized by supplementing masks’ textile structure with virus protective coatings. Therefore, in this concept suitable techniques for manufacturing virus protective filter media should be evaluated. In this study, nonwoven polyamide 6 (PA6) filter material are functionalized with negatively charged linear polyglycerol sulfate (LPGS) as a virus binding functional group. Two coating conditions are investigated in which the direct covalent coating with LPGS has emerged as the optimum coating method, showing no damage to the PA6 nanofibers structure. The uncoated PA6 and LPGS-coated PA6 filter materials exhibited virus particle filtration efficiencies of 95% and 94% for airborne feline coronavirus, 98% and 86% for airborne equine herpesvirus 1(EHV-1), respectively. However, the SARS-CoV-2 absorption assay in solution indicates that the LPGS coating reducing viral titres up to 71% when incubating with the LPGS-coated PA6 filter media for one-hour. Thus, such effect is not seen for uncoated PA6 materials. These findings confirm the suitability of LPGS coating as a suitable platform for suppression the spreading of viruses in different pandemics.