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1. Synthesis and biological evaluation of a novel 99mTc cyclopentadienyl tricarbonyl complex ([(Cp-R) 99mTc (CO) 3]) for sigma-2 receptor tumor imaging

Xin Chen, Meng-Chao Cui, Winnie Deuther-Conrad, Ying-Feng Tu, Teng Ma, Ying Xie, Bing Jia, Yan Li, Fang Xie, Xia Wang, Jörg Steinbach, Peter Brust, Bo-Li Liu, Hong-Mei Jia – 2012

We report the design, synthesis and biological evaluation of a novel 99m Tc 4-(4-cyclohexylpiperazine-1-yl)-butan-1-one-1-cyclopentadienyltricarbonyl technetium ([99mTc]5) as a potential SPECT tracer for imaging of r2 receptors in tumors.

Title
1. Synthesis and biological evaluation of a novel 99mTc cyclopentadienyl tricarbonyl complex ([(Cp-R) 99mTc (CO) 3]) for sigma-2 receptor tumor imaging
Author
Xin Chen, Meng-Chao Cui, Winnie Deuther-Conrad, Ying-Feng Tu, Teng Ma, Ying Xie, Bing Jia, Yan Li, Fang Xie, Xia Wang, Jörg Steinbach, Peter Brust, Bo-Li Liu, Hong-Mei Jia
Date
2012
Identifier
doi.org/10.1016/j.bmcl.2012.08.083
Citation
Bioorg. Med. Chem. Lett., 22 (2012), pp. 6352-6357
Type
Text