M.Sc. Wiktor Burdzinski
Wiktor studied biochemistry at the Freie Universität Berlin and performed his Master thesis in the Signal Transduction group of Prof. Petra Knaus. During his Master thesis, Wiktor established receptor and growth factor staining techniques for visualization of BMP/TGFβ receptor complexes in super resolution microscopy.
In May 2021 Wiktor received a scholarship and became a member of the Berlin Brandenburg School of Regenerative Therapies at the Charité Universitätsmedizin Berlin to pursue his scientific career as a PhD candidate in the group of Petra Knaus.
In his PhD project, Wiktor focusses on the molecular characterization of a hyper‑sensitive receptor complex encompassing the mutated receptor ALK2-R206H, which drives the formation of heterotopic ossification in the rare disease Fibrodysplasia Ossificans Progressiva (FOP).
Wiktor participates as a tutor in the lipid and membrane biochemistry practical course for Bachelor students at the Biochemistry department of the Freie Universität Berlin.
Biochemistry
PhD Candidate
Signal Transduction
Biochemisches Blockpraktikum (BBP)- Lipide und Membranen
Jatzlau J*, Burdzinski W*, Trumpp M, Obendorf L, Roßmann K, Ravn K, Hyvönen M, Bottanelli F, Broichhagen J, Knaus P. A versatile Halo- and SNAP-tagged BMP/TGFβ receptor library for quantification of cell surface ligand binding. Commun Biol. 2023 Jan 12. DOI: 10.1038/s42003-022-04388-4.
Mendez PL, Obendorf L, Jatzlau J, Burdzinski W, Reichenbach M, Nageswaran V, Haghikia A, Stangl V, Hiepen C, Knaus P. Atheroprone fluid shear stress-regulated ALK1-Endoglin-SMAD signaling originates from early endosomes. BMC Biol. 2022 Sep 28. DOI: 10.1186/s12915-022-01396-y.
Brunner P, Hastar N, Kaehler C, Burdzinski W, Jatzlau J, Knaus P. AMOT130 drives BMP-SMAD signaling at the apical membrane in polarized cells. Mol Biol Cell. 2020 Jan 15. DOI: 10.1091/mbc.E19-03-0179.