Werner S., Bartrina, I., Schmülling T. (2021) Cytokinin regulates vegetative phase change in Arabidopsis thaliana through the miR172/TOE1-TOE2 module. Nature Communications 12, 5816. https://doi.org/10.1038/s41467-021-26088-z
- Cytokinin action through transcriptional regulation
Great part of the cytokinin signaling output is realized through the altered expression of cytokinin response genes. This is achieved through B-type response regulators (RRBs), which are transcription factors (TFs) of the Myb family. Interaction of RRBs with other TFs contributes to the variability and the specification of the transcriptional output. We have carried out a genome-wide yeast two-hybrid interaction screen of Arabidopsis RRBs with other TFs and are currently exploring the biological significance of some of these interactions. This project is led by Jan Erik Leuendorf.
Interaction of different transcription factors
modulates the transcriptional response to cytokinin.