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Kinetic models from experiment

HMM of the folding process of Diels-Alderase

HMM of the folding process of Diels-Alderase

  • C. Manz, A. Y. Kobitski, A. Samanta, B. G. Keller, A. Jäschke,  G. U. Nienhaus, “Single-molecule FRET reveals the energy landscape of the full-length SAM-I riboswitch,” Nat. Chem. Biol.,  441, 1172 (2017)
  • B. G. Keller, A. Kobitski, A. Jäschke, G. U. Nienhaus,  F. Noé, “Complex RNA Folding Kinetics Revealed by Single-Molecule FRET and Hidden Markov Models,” J. Am. Chem. Soc.,  136, 4534–4543 (2014)
  • B. G. Keller, J.-H. Prinz,  F. Noé, “Markov models and dynamical fingerprints: Unraveling the complexity of molecular kinetics,” Chem. Phys.,  396,  92–107  (2012)
  • B. G. Keller, J. H. Prinz,  F. Noé, “Resolving the apparent gap in complexity between simulated and measured kinetics of biomolecules,” From Computational Biophysics to Systems Biology (CBSB11). Proceedings, 20-22 July 2011, Jülich Germany. IAS Series, 8, 61-64 (2012)
  • J. D. Chodera, P. Elms, F. Noé, B. Keller, C. M. Kaiser, A. Ewall-Wice, S. Marqusee, C. Bustamante,  N. S. Hinrichs, “Bayesian hidden Markov model analysis of single-molecule force spectroscopy: Characterizing kinetics under measurement uncertainty,” arXiv, arXiv:1108.1430 (2011)