Controlling the Assembly of Cellulose-Based Oligosaccharides through Sequence Modifications
N. Hribernik, D. Vargova, M. C. S. Dal Colle, J. H. Lim, G. Fittolani, Y. Yu, J. Fujihara, K. Ludwig, P. H. Seeberger, Y. Ogawa and M. Delbianco – 2023
Peptides and nucleic acids with programmable sequences are widely explored for the production of tunable, self-assembling functional materials. Herein we demonstrate that the primary sequence of oligosaccharides can be designed to access materials with tunable shapes and properties. Synthetic cellulose-based oligomers were assembled into 2D or 3D rod-like crystallites. Sequence modifications within the oligosaccharide core influenced the molecular packing and led to the formation of square-like assemblies based on the rare cellulose IV(II) allomorph. In contrast, modifications at the termini generated elongated aggregates with tunable surfaces, resulting in self-healing supramolecular hydrogels.
Title
Controlling the Assembly of Cellulose-Based Oligosaccharides through Sequence Modifications
Author
N. Hribernik, D. Vargova, M. C. S. Dal Colle, J. H. Lim, G. Fittolani, Y. Yu, J. Fujihara, K. Ludwig, P. H. Seeberger, Y. Ogawa and M. Delbianco
Date
2023
Identifier
DOI: 10.1002/anie.202310357, DOI: 10.1002/ange.202310357
Citation
Angew Chem Int Ed Engl 2023, e202310357
Language
eng
Type
Text