Enantioselective Dichlorination of Allylic Alcohols
K.C. Nicolaou, N.L. Simmons, Y. Ying, P. Heretsch, J.S. Chen – 2011
The development of an enantioselective allylic alcohol dichlorination catalyzed by dimeric cinchona alkaloid derivatives and employing aryl iododichlorides as chlorine sources is reported. Reaction optimization, exploration of the substrate scope, and a model for stereoinduction are presented.