C–H-Functionalization logic guides the synthesis of a carbacyclopamine analog
S. Rabe, J. Moschner, M. Bantzi, P. Heretsch, A. Giannis – 2014
The chemical synthesis of carbacyclopamine analog 2, a cyclopamine analog with an all-carbon E-ring, is reported. The use of C–H-functionalization logic and further metal-catalyzed transformations allows for a concise entry to this new class of acid-stable cyclopamine analogs.
Title
C–H-Functionalization logic guides the synthesis of a carbacyclopamine analog
Author
S. Rabe, J. Moschner, M. Bantzi, P. Heretsch, A. Giannis
Date
2014
Identifier
DOI: 10.3762/bjoc.10.161
Source(s)
Citation
Beilstein J. Org. Chem. 2014, 10, 1564-1569