Springe direkt zu Inhalt

6. Beyond the Isoprene Pattern: Bifunctional Polyene Cyclizations (Perspective)

J. M. Feilner°, F.-L. Haut°, T. Magauer* (°= equal contributions)

Polyene cyclizations are capable of producing molecular complexity in a single step. While classical systems are limited to simple alkyl substitution patterns only, bifunctional polyenes take advantage of the unique reactivity of higher-functionalized alkenes. Here, we highlight the potential of these variants for the synthesis of structurally complex polycycles involving unprecedented termination steps. We also want to provide a stimulus for the development of novel modes of cyclization that involve bifunctional units to enable efficient synthesis of yet inaccessible natural products.

Title
6. Beyond the Isoprene Pattern: Bifunctional Polyene Cyclizations (Perspective)
Author
J. M. Feilner°, F.-L. Haut°, T. Magauer* (°= equal contributions)
Citation
Chem. Eur. J. 2021, 27, 7017–7021
Type
Text