54. Herstellung von polyzyklischen Diterpenen
R. Janke, M. Fuchs, M. Christmann, T. Brück, B. Loll
Diterpenes constitute a versatile class of natural biomolecules predominantly derived from plants, fungi and prokaryotes. Properties of these natural products include anti-tumour, anti-inflammatory, antibiotic, and insecticidal activities, which makes these compounds high value commercial targets for the chemical and pharmaceutical industry. Since chemical synthesis of terpenes can be difficult, production can be alternatively performed in engineered microorganisms on natural occurring routes.