31. One-Pot Reactions Accelerate the Synthesis of Active Pharmaceutical Ingredients
C. Vaxelaire, P. Winter, M. Christmann
All in one: A one-pot synthesis of the dipeptidylpeptidase IV selective inhibitor ABT-341 (see structure) by using an “uninterrupted sequence of reactions” has been developed. This strategy broadens the spectrum of one-pot reactions and is poised to speed up the synthesis of medicinally relevant drug compounds.