Springe direkt zu Inhalt

pH-sensitive supramolecular copolydendrimers, new anticancer drug delivery system

B. Khodadadi Chegeni, A. Kakanejadifard, F. Abedi, R. Kabiri, F. Daneshnia, M. Adeli – 2014

In this work, new class of supramolecular copolydendrimers (SCDs) consisting of polyamidoamines (PAMAMs) and polyglycerol were synthesized through host-guest interactions. SCDs were able to encapsulate, transport, and release doxorubicin (DOX) efficiently. Host-guest interactions between PAMAM and polyglycerol was depended on pH so that aqueous solutions of SCDs and SCDs-based drug delivery systems were stable at room temperature and pH = 7.4, but their building blocks were separated in lower pHs(

Title
pH-sensitive supramolecular copolydendrimers, new anticancer drug delivery system
Author
B. Khodadadi Chegeni, A. Kakanejadifard, F. Abedi, R. Kabiri, F. Daneshnia, M. Adeli
Date
2014
Identifier
10.1007/s00396-014-3398-2
Citation
Colloid Polym Sci., 2014, 292 (12), 3337-3346
Type
Text