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Hybrid Nanomaterials containing PAMAM, Polyrotaxane and Quantum Dot Blocks

Mohsen Adeli, Reza Sadeghi Sarabi, and Elham Sadeghi – 2011

Pseudopolyrotaxanes, Ps-PR, consisting of α-cyclodextrin rings, polyethylene glycol axes and end triazine groups were prepared and then were capped by amino-functionalized quantum dots, NH2-QDs, to achieve polyrotaxanes. The amino-functionalized QDs stoppers of polyrotaxanes were used as core to synthesize polyamidoamine, PAMAM, dendrons divergently and hybrid nanomaterials were obtained. Synthesized hybrid nanomaterials were characterized by different spectroscopy, microscopy and thermal analysis methods. They were freely soluble in water and their aqueous solutions were stable at room temperature over several months. Due to their biocompatible backbone, high functionality and water solubility synthesized hybrid nanomaterials are promising carriers and probes in cancer diagnosis and therapy.

Title
Hybrid Nanomaterials containing PAMAM, Polyrotaxane and Quantum Dot Blocks
Author
Mohsen Adeli, Reza Sadeghi Sarabi, and Elham Sadeghi
Date
2011
Identifier
10.1142/S1793292011002561
Citation
Nano, 2011, 6 (3), 239-249
Type
Text