Springe direkt zu Inhalt

Noncovalent interactions between Linear-dendritic copolymers and Carbon nanotubes; a promising way to avoid the asbestos-like pathology of long carbon nanotubes

M. Adeli, S. Beyranvand, M. Hamid – 2012

Morphology (conformation) of carbon nanotubes was changed from extended- toward closed-state upon noncovalent interactions with polyglycerol-poly(ethylene glycol)-polyglycerol ABA type hydrophilic linear-dendritic copolymer and liposome-like nanocapsules were formed. Since one of the proposed reasons for the carcinogenicity of carbon nanotubes is their long lengths and rigid structures, flexible liposome-like nanocapsules prepared by this strategy could be safer and far from the asbestoslike physicochemical properties of CNTs and therefore their potential health hazards. Avoiding these health hazards, it is possible to develop CNTs for biomedical applications. Therefore biocompatibility of liposome-like nanocapsules and their ability to load and deliver anticancer drugs such as doxorubicin was evaluated and it was proved that their loading capacity is more that two grams of drug to one gram of liposome-like nanocapsules.

Title
Noncovalent interactions between Linear-dendritic copolymers and Carbon nanotubes; a promising way to avoid the asbestos-like pathology of long carbon nanotubes
Author
M. Adeli, S. Beyranvand, M. Hamid
Date
2012
Identifier
10.1039/c2jm16919c
Citation
J. Mater. Chem., 2012, 22, 6947–6952
Type
Text