A Very Strong Methylation Agent: [Me₂Cl][Al(OTeF₅)₄]
Me2Cl
097
Sebastian Hämmerling, Günther Thiele, Simon Steinhauer, Helmut Beckers, Carsten Müller, Sebastian Riedel – 2019
A new chloronium‐containing salt, [Me₂Cl][Al(OTeF₅)₄], was synthesized on multigram scale by means of a simple one‐pot procedure. The isolated product can be handled at room temperature and used as a strong electrophilic methylation agent. This is demonstrated by the methylation of the very weak bases P(CF₃)₃, PF₃, MeI, and MeBr.
Title
A Very Strong Methylation Agent: [Me₂Cl][Al(OTeF₅)₄]
Author
Sebastian Hämmerling, Günther Thiele, Simon Steinhauer, Helmut Beckers, Carsten Müller, Sebastian Riedel
Date
2019
Source(s)
Appeared in
Angew. Chem. Int. Ed. 2019, 58, 29, 9807-9810
Angew. Chem. 2019, 131, 29, 9912-9915 HOT Paper
Citation
DOI: 10.1002/anie.201904007
DOI: 10.1002/ange.201904007
Language
eng