CV: 

Since 05/2023: SFB/CRC-associated group leader at the Freie Universität Berlin, institute for chemistry and biochemistry, Berlin, Germany

 2019-2023: Post-doctoral researcher in the group of Lori Passmore at the Medical Research Council Laboratory of Molecular Biology (MRC-LMB), Cambridge, United Kingdom

 2016-2019: Post-doctoral researcher in the group of Markus C Wahl at the Freie Universität Berlin, Berlin, Germany

 2011-2016 Doctoral researcher in the group of Markus C Wahl at the Freie Universität Berlin, Berlin, Germany

 2008-2010: Master of Science, Technische Universität München, Munich, Germany

 2005-2008: Bachelor of Science, Technische Universität München, Munich, Germany

1. Absmeier E*, Chandrasekaran V*, O´Reilly FJ, Stowell JAW, Rappsilber J, Passmore LA (2023) Specific recognition and ubiquitination of translating ribosomes by mammalian CCR4-NOT. Nature Structural & Molecular Biology 30(9):1314-1322, DOI: 10.1038/s41594-023-01075-8
2. Höpfler M, Absmeier E, Peak-Chew SY, Vartholomaiou E, Passmore LA, Gasic I, Hegde RS (2023) Mechanism of ribosome-associated mRNA degradation during tubulin autoregulation. Molecular Cell, 83(13):2290-2302.e13, DOI:10.1016/j.molcel.2023.05.020
3. Absmeier E*, Vester K*, Ghane T, Burakovskiy D, Milon P, Imhof P, Rodnina MV, Santos KF*, Wahl MC (2021) Long-range allostery mediates cooperative adenine nucleotide binding by the Ski2-like RNA helicase Brr2. J Biol Chem, 297., DOI: 10.1016/j.jbc.2021.100829
4. Jia J, Absmeier E, Holton N, Pietrzyk-Brzezinska AJ, Hackert P, Bohnsack KE, Bohnsack MT, Wahl MC (2020) The interaction of DNA repair factors ASCC2 and ASCC3 is affected by somatic cancer mutations. Nature Communications, 11, 5535., DOI: 10.1038/s41467-020-19221-x
5. Jia J, Ganichkin OM, Preußner M, Absmeier E, Alings C, Loll B, Heyd F, Wahl MC (2020) A Snu114–GTP–Prp8 module forms a relay station for efficient splicing in yeast. Nucleic Acid Research, 48, 4572-4584.,
6. DOI: 10.1093/nar/gkaa182
7. Absmeier E*^,#, Santos KF*, Wahl MC (2020) Molecular Mechanism Underlying Inhibition of Intrinsic ATPase Activity in a Ski2-like RNA Helicase. Structure, 28, 236-243., DOI: 10.1016/j.str.2019.11.014
8. Pietrzyk-Brzezinska AJ, Absmeier E, Klauck E, Wen Y, Antelmann H, Wahl MC (2018) Crystal Structure of the Escherichia coli DExH-Box NTPase HrpB. Structure 26, 1462-1473., DOI: 10.1016/j.str.2018.07.013
9. Absmeier E, Becke C, Wollenhaupt J, Santos KF, Wahl MC (2017) Interplay of cis- and trans-regulatory mechanisms in the spliceosomal RNA helicase Brr2. Cell Cycle16, 100-112., DOI: 10.1080/15384101.2016.1255384
10. Absmeier E, Wollenhaupt J, Mozaffari-Jovin S, Becke C, Lee CT, Preussner M, Heyd F, Urlaub H, Lührmann R, Santos KF, Wahl MC (2015) The large N-terminal region of the Brr2 RNA helicase guides productive spliceosome activation. Genes & Development 29, 2576-2587. Cover story, DOI: 10.1101/gad.271528.115
11. Absmeier E, Rosenberger L, Apelt L, Becke C, Santos KF, Stelzl U, Wahl MC (2015) A non-canonical PWI domain in the N-terminal helicase-associated region of the spliceosomal Brr2 protein. Acta Crystallogr D 71, 762-771., DOI: 10.1107/S1399004715001005

*equal contribution, ^#co-corresponding