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The δ subunit and NTPase HelD institute a two-pronged mechanism for RNA polymerase recycling
A skipping rope translocation mechanism in a widespread family of DNA repair helicases Roske in Nucleic Acids Research
Loll in JACS: The Impression of a Nonexisting Catalytic Effect: The Role of CotB2 in Guiding the Complex Biosynthesis of Cyclooctat-9-en-7-ol
Steps toward translocation-independent RNA polymerase inactivation by terminator ATPase ρ
Neumann in EMBO Reports Neumann, Heyd, Preußner - Alternative splicing coupled mRNA decay shapes the temperature‐dependent transcriptome
Stricker in Journal of Cachexia, Sarcopenia and Muscle: Cell autonomous requirement of neurofibromin (Nf1) for postnatal muscle hypertrophic growth and metabolic homeostasis
Hiepen, Mendes, Knaus in Cells: "It Takes Two to Tango: Endothelial TGFβ/BMP Signaling Crosstalk with Mechanobiology"
Huang - Structure-Based Mechanisms of a Molecular RNA Polymerase/Chaperone Machine Required for Ribosome Biosynthesis
Freund in Brain Syntaxin-1B mutations reveal clear molecular disease mechanisms that translate into distinct neurophysiological phenotypes
Knaus in Bone BMP signalling in a mechanical context – Implications for bone biology
Meinke et al, in eLife Srsf10 and the minor spliceosome control tissue-specific and dynamic SR protein expression
Tom Haltenhof et al. in Molecular Cell: A conserved kinase-based body temperature sensor globally controls alternative splicing and gene expression
Knaus-AMOT130 drives BMP-SMAD signaling at the apical membrane in polarized cells
Hiepen-BMPR2 acts as a gatekeeper to protect endothelial cells from increased TGFβ responses and altered cell mechanics
Chakrabarti - Insights into the assembly and architecture of a Staufen-mediated mRNA decay (SMD)-competent mRNP
Loll - Current understanding and biotechnological application of the bacterial diterpene synthase CotB2
Wahl - Structural basis for the function of SuhB as a transcription factor in ribosomal RNA synthesis
Freund - Exon Inclusion Modulates Conformational Plasticity and Autoinhibition of the Intersectin 1 SH3A Domain
Stauber - A FRET sensor of C-terminal movement reveals VRAC activation by plasma membrane DAG signaling rather than ionic strength
F. De Bortoli - Increased versatility despite reduced molecular complexity: evolution, structure and function of metazoan splicing factor PRPF39
A. Neumann - Genome-wide identification of alternative splicing events that regulate protein transport across the secretory pathway
J. Sticht - FBP21’s C-Terminal Domain Remains Dynamic When Wrapped around the c-Sec63 Unit of Brr2 Helicase
R. Driller - Towards a comprehensive understanding of the structural dynamics of a bacterial diterpene synthase during catalysis
S. Stricker - Odd skipped-related 1 (Osr1) identifies muscle-interstitial fibro-adipogenic progenitors (FAPs) activated by acute injury
B. Loll - Molecular insights into antibiotic resistance - how a binding protein traps albicidin
S. Stricker - Genome-wide strategies identify downstream target genes of connective tissue-associated transcription factors
Sigmar Stricker - Cooperation of BMP and IHH signaling in interdigital cell fate determination
Jan Wollenhaupt - Intrinsically Disordered Protein Ntr2 Modulates the Spliceosomal RNA Helicase Brr2
B. Loll: Ketonization of Proline Residues in the Peptide Chains of Actinomycins by a 4-Oxoproline Synthase
B. Loll: Rhodococcus erythropolis Oleate Hydratase: a New Member in the Oleate Hydratase Family Tree
210104 Pei in Nature Communications
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Roske in Nucleic Acids Research
201208 Loll in JACS
Image Credit: JACS
Said in Science
201123 Preussner in EMBO Reports
Nf1
Hiepen in Cell
200930Huang
Freund-in-Brain
Knaus in Bone
Meinke et al in eLife
Haltenhof in Molecular Cell
200201-Knaus in MBC of the cell
Image Credit: MBC of the cell
200114-Hiepen in PLOS Biol
Image Credit: PLOS
191108-Sutapa
Loll in Beilstein J Org Chem
091019-Wahl-Nucleic Acids Res
190910-Freund
190627-Stauber-eLIFE
Image Credit: T. Stauber
190416 Francesca PRPF39 structure
Image Credit: DeBortoli
neumann_zelle1-3
Image Credit: Alex Neumann
190212-Jana-Sticht-Feb-2019-a
Image Credit: Sticht/Biophysical Journal
Driller/Nature Communications
Image Credit: Driller/Nature Communications
070918-Stricker
Image Credit: Stricker/Stem Cell Research
180809-Loll
Image Credit: B. Loll/Nature Communications
080818-Stricker
Image Credit: S. Stricker/Development
070818-Stricker-PLoS
Image Credit: S. Stricker/PLoS one
online access
Image Credit: J. Wollenhaupt
Image Credit: B. Loll
