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Rececent Research

Huang in Molecular Cell

Huang - Structure-Based Mechanisms of a Molecular RNA Polymerase/Chaperone Machine Required for Ribosome Biosynthesis

Freund in Brain

Freund in Brain
Syntaxin-1B mutations reveal clear molecular disease mechanisms that translate into distinct neurophysiological phenotypes

Knaus in Bone

Knaus in Bone
BMP signalling in a mechanical context – Implications for bone biology

Meinke in eLife

Meinke et al, in eLife
Srsf10 and the minor spliceosome control
tissue-specific and dynamic SR protein expression

Haltenhof in Molecular Cell

Tom Haltenhof et al. in Molecular Cell: A conserved kinase-based body
temperature sensor globally controls alternative splicing and gene
expression

Knaus in MBC of the cell

Knaus-AMOT130 drives BMP-SMAD signaling at the apical membrane in polarized cells

Hiepen in PLOS Biology

Hiepen-BMPR2 acts as a gatekeeper to protect endothelial cells from increased TGFβ responses and altered cell mechanics

Chakrabarti in Nature Communications

Chakrabarti - Insights into the assembly and architecture of a Staufen-mediated mRNA decay (SMD)-competent mRNP

Loll in Beilstein J Org Chem

Loll - Current understanding and biotechnological application of the bacterial diterpene synthase CotB2

Wahl in Nucleic Acids Research

Wahl - Structural basis for the function of SuhB as a transcription factor in ribosomal RNA synthesis

Freund in Structure

Freund - Exon Inclusion Modulates Conformational Plasticity and Autoinhibition of the Intersectin 1 SH3A Domain

Stauber in eLIFE

Stauber - A FRET sensor of C-terminal movement reveals VRAC activation by plasma membrane DAG signaling rather than ionic strength

DeBortoli in Nucleic Acids Research

F. De Bortoli - Increased versatility despite reduced molecular complexity: evolution, structure and function of metazoan splicing factor PRPF39

Neumann in Journal of Cell Science

A. Neumann - Genome-wide identification of
alternative splicing events that regulate protein transport across the
secretory pathway

Sticht in Biophysical Journal

J. Sticht - FBP21’s C-Terminal Domain Remains Dynamic When Wrapped around the c-Sec63 Unit of Brr2 Helicase

Driller in Nature Communications

R. Driller - Towards a comprehensive understanding of the
structural dynamics of a bacterial diterpene
synthase during catalysis

Stricker in Stem Cell Research

S. Stricker - Odd skipped-related 1 (Osr1) identifies muscle-interstitial fibro-adipogenic progenitors (FAPs) activated by acute injury

Loll in Nature Communications

B. Loll - Molecular insights into antibiotic resistance - how a binding protein traps albicidin

Stricker in Development

S. Stricker - Genome-wide strategies identify downstream target genes of connective tissue-associated transcription factors

Stricker in PLoS ONE

Sigmar Stricker - Cooperation of BMP and IHH signaling in interdigital cell fate determination

Wollenhaupt in Biophysical Journal

Jan Wollenhaupt - Intrinsically Disordered Protein Ntr2 Modulates the Spliceosomal RNA Helicase Brr2

Loll in ChemBioChem

B. Loll: Ketonization of Proline Residues in the Peptide Chains of Actinomycins by a 4-Oxoproline Synthase

Loll in ChemCatChem

B. Loll: Rhodococcus erythropolis Oleate Hydratase: a New Member in the Oleate Hydratase Family Tree