Systematic discovery of Rab GTPases with synaptic functions in Drosophila.

Chan, C.C., Scoggin, S., Wang, D., Cherry, S., Dembo, T., Greenberg, B., Jin, E.J., Kuey, C., Lopez, A., Mehta, S.Q., Perkins, T.J., Brankatschk, M., Rothenfluh, A., Buszczak, M.*, and Hiesinger, P.R.* – 2011

Neurons require highly specialized intracellular membrane trafficking, especially at synapses. Rab GTPases are considered master regulators of membrane trafficking in all cells, and only very few Rabs have known neuron-specific functions. Here, we present the first systematic characterization of neuronal expression, subcellular localization, and function of Rab GTPases in an organism with a brain.

Titel
Systematic discovery of Rab GTPases with synaptic functions in Drosophila.
Verfasser
Chan, C.C., Scoggin, S., Wang, D., Cherry, S., Dembo, T., Greenberg, B., Jin, E.J., Kuey, C., Lopez, A., Mehta, S.Q., Perkins, T.J., Brankatschk, M., Rothenfluh, A., Buszczak, M.*, and Hiesinger, P.R.*
Verlag
Cell Press
Datum
2011-10-13
Kennung
doi: 10.1016/j.cub.2011.08.058
Erschienen in
Curr. Biol. 21(20): 1704-15
Sprache
eng
Art
Text
Rechte
© 2011 Elsevier Ltd.
NeuroCure