Early-career postdoctoral researcher with a fellowship from the Alexander von Humboldt foundation.

 Education

Faculty of Pharmacy, Cairo University, Cairo, Egypt

PhD in Pharmacy (Pharmacology and Toxicology), July 2022

MSc in Pharmacy (Pharmacology and Toxicology), December 2018

BSc in Clinical Pharmacy, May 2013

• Employment

Faculty of Pharmacy, Cairo University, Cairo, Egypt, March 2014 – present

Lecturer at the Department of Pharmacology and Toxicology (October 2022 − present).

Assistant lecturer at the Department of Pharmacology and Toxicology (March 2019 − September 2022).

Teaching assistant at the Department of Pharmacology and Toxicology (March 2014 − March  2019).

• Current research project
  

  Working on the study proposal “Novel insights for management of ischaemic stroke outcomes through repurposing of approved antidiabetic SGLT2 inhibitors” with the involvement of a research team from the Department of Pharmacology and Toxicology at the Institute of Pharmacy, Freie Universität Berlin under the supervision of Prof. Dr. Burkhard Kleuser.

• Research interest

Cardiology, Oncology, and CNS research

• Awards

- Alexander von Humboldt (Georg Forster) postdoctoral research fellowship at FUB (2025)

- Best PhD thesis in 2022 at the Department of Pharmacology and Toxicology, Faculty of Pharmacy, Cairo University

- Muhammad, R.N., Aborehab, N.M., Aly, S.H. et al. Natural products as HMG-CoA reductase inhibitors (statins) for the management of non-communicable diseases. Inflammopharmacol (2025). https://doi.org/10.1007/s10787-025-02069-2.

 - Sharaf AM, Muhammad RN, Khalifa HO, Kandil EA, Ahmed LA. Metoprolol exacerbates dementia in scopolamine-induced cognitive impairment in rats: A potential role of NADPH oxidase. Neuropharmacology. 2025 Dec 1;280:110657. doi: 10.1016/j.neuropharm.2025.110657. Epub 2025 Aug 24. 

- Shafik MS, El-Tanbouly DM, Bishr A, Soubh AA, Attia AS, Muhammad RN. Activation of Sig-1R by afobazole attenuates Tollip/HMGB1-mediaded CCN2 autophagic degradation and NETs formation in sunitinib-induced cardiotoxicity in mice: Involvement of IRE 1α/ASK1/JNK/ AP-1 trajectory. Toxicol Appl Pharmacol. 2025 Sep;502:117423. doi:10.1016/j.taap.2025.117423. Epub 2025 May 29. 

- Muhammad R.N., Albahairy M.A., Abd El Fattah M. A. Empagliflozin-activated AMPK elicits neuroprotective properties in reserpine-induced depression via regulating dynamics of hippocampal autophagy/inflammation and PKCζ-mediated neurogenesis. Psychopharmacology (2024). DOI: 10.1007/s00213-024-06663-0

- Muhammad, R.N., Ahmed, L.A., Abdul Salam, R.M. et al. Crosstalk Among NLRP3 Inflammasome, ETBR Signaling, and miRNAs in Stress-Induced Depression-Like Behavior: A Modulatory Role for SGLT2 Inhibitors. Neurotherapeutics (2021). https://doi.org/10.1007/s13311-021-01140-4

- Muhammad, R.N., Sallam, N. & El-Abhar, H.S. Activated ROCK/Akt/eNOS and ET-1/ERK pathways in 5-fluorouracil-induced cardiotoxicity: modulation by simvastatin. Sci Rep 10, 14693 (2020). https://doi.org/10.1038/s41598-020-71531-8