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Summer BBQ at Kelchstr.
On 9 August 2022, our Department will enjoy the lovely season together through a summer BBQ.
PharMetrX Module Curriculum continues with A3 module
From 01 – 05 Aug 2022, the PharMetrX A3 module “Introduction to Population Analysis” will take place at the FU Berlin. For more detailed information on the module and the structured Graduate Research Training program PharMetrX, please visit our homepage www.PharMetrx.de.
We participate in the 12th Scientific Symposium “Young scientists present” of our Institute
On 08 July 2022, our Institute of Pharmacy together with the DPhG (German Pharmaceutical Society, Deutsche Pharmazeutische Gesellschaft Landesgruppe Berlin-Brandenburg), hosts the 12th Scientific Symposium as biyearly event „Der Wissenschaftliche Nachwuchs stellt sich vor – Young scientists present”. 9 young scientists of our and many of the other research groups of the Institute of Pharmacy will present their research in talks and on posters to foster exchange between all research groups at the Institute and attract new master, diploma and doctoral students. We are looking forward to an exciting event and to seeing as many of you there!
Scientific workshop with Prof. Meibohm, UTHSC/USA
On 05 July 2022, Prof. Bernd Meibohm from the University of Tennessee Health Science Center, Memphis, TN, USA, will visit our Department again for a scientific workshop. He will give insights about new aspects of PK/PD of therapeutic proteins. In addition, three members of our working group, Linda Aulin, Davide Bindellini and Alix Démaris will present their research.
Contributions to annual PAGE 2022 meeting
From 28 June to 1 July 2022, the 30th Population Approach Group Europe (PAGE) meeting takes place in Ljubljana, Slovenia. From our Department, Alix Démaris will represent our group through an oral presentation andour young scientists Linda Aulin, Davide Bindellini, Yomna Nassar, Ayatallah Saleh and Ella Widigson through poster presentations.
FAIR annual meeting in Nice/France
From 15 – 16 June 2022, theannual meeting of the FAIR project takes place in Nice, France. From our Department, Prof. Dr. Charlotte Kloft, Dr. Robin Michelet, and Linda Aulin will attend.
We will be at ‘Lung In Vitro event 2022’ (LIVe2022)
From 13 – 14 June 2022, the Lung In Vitro event 2022 – (LIVe2022) takes place in Nice, France. From our Department, Prof. Dr. Charlotte Kloft, Dr. Robin Michelet, and Linda Aulin will represent our group through an oral presentation.
Research Exchange Day with Uppsala University
On 10 June 2022, a research Exchange Day will be organised together with Uppsala University, Sweden. From our group, PhD students Alix Démaris, Fenja Klima and Yomna Nassar will present their research. We are looking forward to fruitful discussion and exchange!
11th PharMetrX Symposium
On 02 May 2022, the 11th PharMetrX Symposium 2022 will take place (online). Two PharMetrX Research+ doctoral students, Alix Démaris and Daniel Seeler, will present their scientific work. For more detailed information on the structured Graduate Research Training program PharMetrX, please visit our homepage www.PharMetrx.de
The AK Kloft is glad to welcome a new member
In May 2022, a new guest visitor as ERASMUS+ student, Zrinka Duvnjak joined our Department. Zrinka Duvnjak studied pharmacy and obtained her masters at the University of Zagreb, Croatia. She will have her 5-monthsinternship project in the area of modelling and simulation. A warm WELCOME!
The AK Kloft is glad to welcome a new AvH guest researcher
On the 9th of May 2022, Prof. Dr. Stephan Schmidt joined as Alexander-von-Humboldt Research Fellow our Department as a guest researcher. He is an Associate Professor in the Department of Pharmaceutics and Director of the Center for Pharmacometrics and Systems Pharmacology at the University of Florida, US. In our group Prof. Dr. Schmidt will focus on QSP and mechanistic modelling.
A warm WELCOME!
24th PK/PD Expert Meeting
From 28-30 April 2022, the 24th PK/PD Expert Meeting will take place at Saarland University, Saarbrücken. Presentations and associated discussions will focus on the topics “Machine learning: From Buzzword to Useful Tool in Clinical Pharmacology?”, “Precision Dosing - Bringing Models to Patients” and “Neglected majorities - What do we have to consider?”. From our Department, Prof. Dr. Charlotte Kloft, Dr. Robin Michelet and the PhD students Alix Démaris, Ayatallah Saleh will attend the meeting. For more information: see www.pkpd-expertentreffen.de
Quantitative Systems Pharmacology Conference 2022 (QSPC2022)
From 20 – 22 April 2022, the Quantitative Systems Pharmacology Conference 2022 (QSPC2022) takes place in Leiden, the Netherlands. One member of our Department, Linda Aulin represents our group through a poster presentations.
New article on cortisol concentrations monitoring in paediatric patients
The research article “Exploring dried blood spot cortisol concentrations as an alternative for monitoring pediatric adrenal insufficiency patients: A model-based analysis“ by Stachanow et al. has been accepted in Frontiers in Pharmacology, and is now available online.
32nd Congress of Clinical Microbiology & Infectious Diseases (ECCMID)
From 23 - 26 April 2022, the 32nd European Congress of Clinical Microbiology & Infectious Diseases (ECCMID) takes place in Lisbon, Portugal. Two members of our Department, Nicole Zimmermann and Malin Andersson will represent our group through poster presentations.
Contributions and symposium at WCoP 2022
From 29 March – 1 April 2022, the 3rd World Conference on Pharmacometrics (WCoP) takes place in Cape Town, South-Africa. Two members of our Department, Dr. Robin Michelet and Prof. Charlotte Kloft will represent our group. They will co-chair a symposium entitled “Training of the next generation of pharmacometric talents around the world: Competencies – Barriers – Opportunities” together with Dr. Stefanie Hennig, Humboldt Research Fellow at our Department.
Pharmacy students joining for a “Schnuppertag”
On 23 March and 4 April, five undergraduate pharmacy students are joining our Department for a short internship, a so-called “Schnuppertag”. They will be getting insight in our working group, research projects and the methodology platform we are using. If you are also interested, please contact Amrei Konrad (firstname.lastname@example.org) for further information
Presentation at ASCPT Annual Meeting 2022
A member of our working group, Anna Mc Laughlin, will present a late-breaking abstract on tamoxifen breast cancer therapy at the American Society for Clinical Pharmacology & Therapeutics (ASCPT) 2022 Annual Meeting, which takes place online. The main topic of the meeting, which takes place from 16-18 March 2022, is “Disruptive innovation”.
PharMetrX Module Curriculum: Kick-off
On 14 March 2021, the PharMetrX Module Curriculum for the new doctoral student year of our PhD program will kick off with the A1 module "Introduction to pharmacokinetics and pharmacodynamics" taking place online from 14 - 21 March 2022. For more detailed information on the module and the structured Graduate Research Training program PharMetrX, please visit our homepage www.PharMetrx.de.
The AK Kloft is glad to welcome a new member
Mid of March 2022, Ella Widigson joined our Department, also being enrolled in our PharMetrX program. Ella studied pharmacy and obtained her M.Sc. atUniversity of Gothenburg, Gothenburg, Sweden. Her doctoral thesis project will focus on pharmacometrics modelling approached of biologics in the area of inflammatory diseases. A warm WELCOME!
New article on metabolism of the antifungal voriconazole
The research article “Towards the Elucidation of the Pharmacokinetics of Voriconazole: A Quantitative Characterization of Its Metabolism“ by Schulz et al. has been published in the Journal Pharmaceutics and is available online.
The AK Kloft is glad to welcome a new member
In March 2022, Fenja Klima joined our Department, also being enrolled in our PharMetrX program. Fenja studied pharmacy at University of Freiburg, Freiburg, Germany. She will have her doctoral thesis project in the area of pharmacometrics of anticancer drugs. A warm WELCOME!
Report on successful joint IPSF & PharMetrX Clinical Skills Event
An article about the Clinical Skills Event (CSE) in November 2021 in collaboration with the International Pharmaceutical Students' Federation (IPSF) is now available in the latest issue of the “Grüne Hand Brief” published by the Federal Association of Pharmacy Students in Germany (BPhD e. V.).The CSE aimed to raise awareness of the importance of the pharmacist's role in clinical patient care. Different teams competed in a friendly environment by demonstrating their skills in clinical pharmacy related project tasks to work out dosing regimens in antibiotic therapy and present their recommendation to the ‘Antibiotic Stewardship team’. Follow-up events are already planned!
New article on meropenem pharmacokinetics in obese and nonobese patiens
The research article “Comparative Plasma and Interstitial Tissue Fluid Pharmacokinetics of Meropenem Demonstrate the Need for Increasing Dose and Infusion Duration in Obese and Non-obese Patients “ by Busse et al. has been accepted in Clinical Pharmacokinetics, and is now available online.
Ethics committee approval for collaboration project
The proposal to the ethics committee for the evaluation of the interprofessional teaching project in collaboration with Charité – Universitätsmedizin Berlin has been accepted.
New article on a model informed dosing tool in antibiotic therapy
The research article “Development of a Model-Informed Dosing Tool to Optimise Initial Antibiotic Dosing—A Translational Example for Intensive Care Units“ by Weinelt et al. has been accepted in Pharmaceutics, and is now available online.
Successful defense of two master theses
Malin Andersson and Ella Widigson successfully defended their master theses, supervised by Prof. Kloft and members of our working group, at University of Gothenburg. Congratulations!
Two abstracts accepted for poster presentation at ECCMID conference
The research abstracts of Nicole Zimmermann and Malin Andersson have been accepted for poster presentation at ECCMID conference in Lisbon and online, 23 – 26 April 2022. Malin Andersson won a travel grant for her excellent abstract. Congratulations!
New article on the optimisation of meropenem therapy in critically ill
The research article “Combination of pharmacokinetic and pathogen susceptibility information to optimize meropenem treatment of gram-negative infections in critically ill patients“ by Liebchen et al. has been accepted in Antimicrobial Agents and Chemotherapy, and is now available online.
New article on review of cost-effectiveness of oral anticancer drugs
The research article “Cost-effectiveness of oral anti-cancer drugs and associated individualised dosing approaches in cancer patients: Protocol for a systematic review and meta-analysis“ by van Dyk et al. has been accepted in the British Medical Journal and is now available online.
New article on evaluating prediction methods for glomerular filtration
Our manuscript “Evaluating prediction methods for glomerular filtration to optimise drug doses in obese and nonobese patients” by Busse et al. has been accepted in the British Journal of Clinical Pharmacology and is now available online.
New article on a LC-MS/MS assay for voriconazole and its N-oxide metabolite
Our manuscript “A versatile high-performance LC-MS/MS assay for the quantification of voriconazole and its N-oxide metabolite in small sample volumes of multiple human matrices for biomedical applications” by Schulz et al. has been accepted in the Journal of Pharmaceutical and Biomedical Analysis and is now available online.
New article on the ON-TARGET study protocol
The manuscript “Developing a nationwide infrastructure for Therapeutic Drug Monitoring of targeted oral anticancer drugs: The ON-TARGET study protocol“ by Mc Laughlin et al. has been accepted in the journal Cancers and is now available online.
PharMetrX at virtual ALARM job fair in Göteborg
PharMetrX at the ALARM job fair 2022 of the University of Gothenburg (GU): We are excited to talk to Pharmacy students of all semesters about our research projects and encourage applying to our do a PhD thesis with us within the Research, Training and Network Graduate Programme! The AK Kloft, represented by Davide Bindellini and Johanna Melin, a current and a former PharMetrX Research+ PhD student, is looking forward to getting in touch with the GU students on the 18 January 2022!
New Berlin University Alliance project proposal approved
AK Kloft is proud to announce that the project proposal entitled “GlobalResist – Forecasting antibiotic resistance evolution – a new approach to address a major issue in global health” has been approved for funding as part of the Grand Challenge Initiative on Global Health of the Berlin University Alliance. For this project, the AK Kloft partners with colleagues from FU, Charité and Technische Universität Berlin to develop a wide-ranging approach to predicting antibiotic resistance, intricately linking different disciplines.