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Original Work (peer-reviewed)

[O124]  Loke S, De La Torre X, Iannone M, La Piana G, Schloerer N, Botre F, Bureik M, Parr MK. Controlled Administration of Dehydrochloromethyltestosterone in Humans: Urinary Excretion and Long-Term Detection of Metabolites for Anti-Doping Purpose. J Steroid Biochem Mol Biol (2021) in press

[O123]  Niebel A, Westendorf L, Krumbiegel F, Hartwig S, Parr MK, Tsokos M. Prevalence and concentrations of new psychoactive substances (NPS) in postmortem hair samples - a 13-year retrospective study. Drug Test Anal (2021) in press

[O122]  Zappe A, Rosenlöcher J, Kohla G, Hinderlich S, Parr MK. Purification and Characterization of Antibodies directed against the α-Gal epitope. BioChem 1 (2021) 81-97 (doi: 10.3390/biochem1020008)

[O121]  Dispas A, Clarke A, Grand-Guillaume Perrenoud A, Losacco LG, Veuthey JL, Gros Q, Molineau J, Noireau A, West C, Salafia F, Zoccali M, Mondello L, Guillen A, Wang J, Zhang K, Jochems P, Schad G, Shinnosuke H, Joseph J, Parr MK, Billemont P, Severino A, Schneider S, Naegele E, Kutscher D, Wikfors R, Black R, Ingvaldson L, Da Silva JO, Bennett R, Regalado EL, Hoang TPT, Touboul D, Nikolova Y, Kamenova-Nacheva M, Dimitrov V, Berger BK, Schug KA, Kerviel-Guillon S, Mauge F, Takahashi M, Izumi Y, Bamba T, Rouvière F, Heinisch S, Guillarme D, Hubert P. Interlaboratory study of a Supercritical Fluid Chromatography method for the determination of pharmaceutical impurities: evaluation of multi-systems reproducibility. J Pharmaceut Biomed (2020) in press

[O120]  Mallock N, Rabenstein A, Gernun S, Laux P, Hutzler C, Karch S, Koller G, Henkler-Stephani F, Parr MK, Pogarell O, Luch A, Rüther T. Nicotine delivery and relief of craving after consumption of European JUUL e-cigarettes prior and after pod modification. Scientific Reports (2021) in press

[O119]  Ambrosio G, Yuliandra T, Wuest B, Mazzarino M, de la Torre X, Botre F, Diel P, Isenmann E, Parr MK. Urinary Elimination of Ecdysterone and its Metabolites following a Single-Dose Administration in Humans. Metabolites 11 (2021) 366 (doi:10.3390/metabo11060366)

[O118]  Loke S, Machalz D, Stoll A, Botre F, Wolber G, Bureik M, Parr MK. Corticosteroid biosynthesis revisited: No direct hydroxylation of pregnenolone by steroid 21-hydroxylase. Front Endocrinol 12 (2021) 633785 (doi: 10.3389/fendo.2021.633785)

[O117]  Mallock N, Rabenstein A, Laux P, Rüther T, Hutzler C, Parr MK, Luch A. Rapid, sensitive and reliable quantitation of nicotine and its main metabolites cotinine and trans-3’-hydroxycotinine by LC-MS/MS: Method development and validation for human plasma. J Chrom B (2021) 122736 in press (doi: 10.1016/j.jchromb.2021.122736)

[O116]  Schmidtsdorff S, Neumann J, Schmidt AH, Parr MK. Analytical lifecycle management for comprehensive and universal nitrosamine analysis in various pharmaceutical formulations by supercritical fluid chromatography J Pharmaceut Biomed 197 (2021) 113960 (doi: 10.1016/j.jpba.2021.113960)

[O115]  Leogrande P, de la Torre X, Jardines D, Parr MK, Marini F, Botrè F. Coupling high-resolution mass spectrometry and chemometrics for the structural characterization of anabolic-androgenic steroids and the early detection of unknown designer structures. Talanta 227 (2020) 122173 (doi: 10.1016/j.talanta.2021.122173)

[O114]  Loke S, Liu L, Wenzel M, Scheffler H, Iannone M, De La Torre X, Schloerer N, Botrè F, Keiler AM, Bureik M, Parr MK. New Insights Into the Metabolism of Methyltestosterone and Metandienone: Detection of Novel a-Ring Reduced Metabolites. Molecules 26 (2021) 1354

[O113]  Chutvirasakul B, Joseph JF, Parr MK, Suntornsuk L. Development and applications of liquid chromatography-mass spectrometry for simultaneous analysis of anti-malarial drugs in pharmaceutical formulations. J Pharmaceut Biomed 195 (2020) 113855 (doi: 10.1016/j.jpba.2020.113855)

[O112]  Stoll A, Iannone M, De Gregorio G, Molaioni F, de la Torre X, Botrè F, Parr MK. Influence of indomethacin on steroid metabolism: Endocrine disruption and confounding effects in urinary steroid profiling of anti-doping analyses. Metabolites 10 (2020) 463 (doi: 10.3390/metabo10110463)

[O111]  Sun Y, Machalz D, Wolber G, Parr MK*, Bureik M. Functional expression of all human sulfotransferases (SULTs) in fission yeast, assay development, and structural models for SULT4A1 and SULT6B1. Biomolecules 10 (2020) 1517 (doi: 10.3390/biom10111517)

[O110]  Kollmeier A, de la Torre X, Müller C, Botrè F, Parr MK. In-depth GC-MS/MS fragmentation analysis of formestane and evaluation of mass spectral discrimination of isomeric 3-keto-4-ene hydroxy steroids. Rapid Commun Mass Spectrom 34 (2020) e8769 (doi: 10.1002/rcm.8937)

[O109]  Stoll A, Iannone M, De Gregorio G, de la Torre X, Molaioni F, Botrè F, Parr MK. Influence of pain killers on the urinary anabolic steroid profile. J Anal Toxicol 44 (2020) 871-879 (doi: 10.1093/jat/bkaa049)

[O108]  Aboushady D, Parr MK*, Hanafi RS. Quality-by-design is a tool for quality assurance in the assessment of enantioseparation of a model active pharmaceutical ingredient. Pharmaceuticals 13 (2020) 364 (doi: 10.3390/ph13110364)

[O107]  Albrecht B, Voronina E, Schipke C, Peters O, Parr MK, Díaz-Hernández MD, Schlörer NE. Pursuing experimental reproducibility: an efficient protocol for the preparation of cerebrospinal fluid samples for NMR-based metabolomics. Metabolites 10 (2020) 251 (doi: 10.3390/metabo10060251)

[O106]  Martinez-Brito D, de la Torre X, Parr MK, Botrè F. Mass spectrometric analysis of 7-oxygenated androst-5-ene structures. Influence in trimethylsilyl derivatives formation. Rapid Commun Mass Spectrom 34 (2020) e8834 (doi: 10.1002/rcm.8834)

[O105]  Kollmeier A, Parr MK. Mass spectral fragmentation analyses of istotopically labelled hydroxy steroids using unit mass resolution gas chromatography – mass spectrometry (GC/EI-MS): a practical approach. Rapid Commun Mass Spectrom (2020) e8769 (doi: 10.1002/rcm.8769)

[O104]  Joseph J, Gronbach L, Garcia-Miller J, Da Silva Cruz L, Wuest B, Keilholz U, Zoschke C, Parr MK. Automated real-time pharmacokinetic profiling in 3D tumor models: a novel approach for personalized medicine. Pharmaceutics 12 (2020) 413 (doi: 10.3390/pharmaceutics12050413)

[O103]  Niebel A, Krumbiegel F, Hartwig S, Parr MK, Tsokos M. Detection and quantification of synthetic cathinones and selected piperazines in hair by LC-MS/MS. Forensic Sci Med Pathol 16 (2020) 32-42 (doi: 10.1007/s12024-019-00209-z)

[O102]  Harps LC, Schipperges S, Bredendiek F, Wüst B, Borowiak A, Parr MK. Two dimensional chromatography mass spectrometry: quantitation of chiral shifts in metabolism of propranolol in bioanalysis. J Chrom A 1617 (2020) 460828 (doi: 10.1016/j.chroma.2019.460828)

[O101]  Ambrosio G, Joseph JF, Wuest B, Mazzarino M, de la Torre X, Diel P, Botre F, Parr MK. Detection and quantitation of ecdysterone in human serum by liquid chromatography coupled to tandem mass spectrometry. Steroids 157 (2020) 108603 (doi: 10.1016/j.steroids.2020.108603)

[O100]  Xhaferaj M, Naegele E, Parr MK. Ion exchange in supercritical fluid chromatography tandem mass spectrometry (SFC-MS/MS): Application for polar and ionic drugs and metabolites in forensic and anti-doping analysis. J Chrom A 1614 (2020) 460726 (doi: 10.1016/j.chroma.2019.460726)

[O99]     Ambrosio G, Wirth D, Joseph JF, Mazzarino M, de la Torre X, Botre F, Parr MK. How reliable is dietary supplement labelling? Experiences from the analysis of ecdysterone supplements. J Pharmaceut Biomed 177 (2020) 112877 (doi: 10.1016/j.jpba.2019.112877)

[O98]     Methling M, Krumbiegel F, Alameri, A, Hartwig S, Parr MK, Tsokos M. Concentrations of antidepressants, antipsychotics, and benzodiazepines in hair samples from postmortem cases. SN Comp Clin Med 2 (2020) 284-300 (doi: 10.1007/s42399-020-00235-x)

[O97]     Parr MK, Ambrosio G, Wuest B, Mazzarino M, De La Torre X, Sibilia F, Joseph JF, Diel P, Botrè F. Targeting the Administration of Ecdysterone in Doping Control Samples. Forensic Tox 38 (2020) 172-184 (doi: 10.1007/s11419-019-00504-y)

[O96]     Stoll A, Loke S, Joseph JF, Machalz D, De La Torre X, Botre F, Wolber G, Bureik M, Parr MK. Fine-mapping of the substrate specificity of human steroid 21-hydroxylase (CYP21A2). J Steroid Biochem Mol Biol 194 (2019) 105446 (doi: 10.1016/j.jsbmb.2019.105446)

[O95]     Isenmann E, Ambrosio G, Joseph JF, Mazzarino M, De La Torre X, Zimmer P, Kazlauskas R, Goebel C, Botrè F, Diel P, Parr MK. Ecdysteroids as non-conventional anabolic agent: performance enhancement by ecdysterone supplementation in humans. Arch Toxicology 93 (2019) 1807-1816 (doi: 10.1007/s00204-019-02490-x)

[O94]     Dyck YFK, Rehm D, Joseph JF, Winkler K, Sandig V, Jabs W, Parr MK. Forced Degradation Testing as Complementary Tool for Biosimilarity Assessment. Bioengineering 6 (2019) 1-13 (doi:10.3390/bioengineering6030062)

[O93]     de la Torre X, Martinez Brito D, Colamonici C, Parr MK, Botrè F. Metabolism of formestane in humans: Identification of urinary biomarkers for antidoping analysis. Steroids 146 (2019) 34-42 (doi: 10.1016/j.steroids.2019.03.005)

[O92]     Linbing F, Joseph JF, Durairaj P, Parr MK, Bureik M. Conversion of chenodeoxycholic acid to cholic acid by human CYP8B1. Biol Chem 400 (2019) 625-628 (doi: 10.1515/hsz-2018-0379)

[O91]     Methling M, Krumbiegel F, Hartwig, S, Parr MK, Tsokos M. Toxicological findings in suicides - frequency of antidepressant and antipsychotic substances. Forensic Sci Med Pathol 15 (2019) 23-30 (doi: 10.1007/s12024-018-0041-4)

[O90]     Assaf J, Kollmeier A, Müller C, Parr MK. Reconsidering mass spectrometric fragmentation in EI-MS - new insights from recent instrumentation and isotopic labelling exemplified by ketoprofen and related compounds. Rapid Commun Mass Spectrom 33 (2019) 215-228 (doi: 10.1002/rcm.8313)

[O89]     Schmidtsdorff S, Schmidt AH, Parr MK. Structure assisted impurity profiling for rapid method development in liquid chromatography. J Chromatogr A 1577 (2018) 38-46 (doi:10.1016/ j.chroma.2018.09.044)

[O88]     Mazzarino M, Khevenhüller-Metsch FL, Fiacco I, Parr MK, de la Torre X, Botrè F. Drug-drug interaction and doping: Effect of non-prohibited drugs on the urinary excretion profile of methandienone. Drug Test Anal 10 (2018) 1554–1565 (doi: 10.1002/dta.2406)

[O87]     Montacir O, Montacir H, Springer A, Hinderlich S, Mahboudi F, Saadati A, Parr MK. Bioengineering of rFVIIa biopharmaceutical and structure characterization for biosimilarity assessment. Bioengineering 5 (2018) 7 (doi:10.3390/bioengineering5010007)

[O86]     Ambrosio G, de la Torre X, Mazzarino M, Parr MK, Botrè FM. Effect of non-prohibited drugs on the phase II metabolic profile of morphine. An in vitro investigation for doping control purposes. Drug Test Anal 10 (2018) 984-994 (doi:1 0.1002/dta.2344)

[O85]     Parr MK, Wuest B, Teubel J, Joseph JF. Splittless hyphenation of SFC with MS by APCI, APPI, and ESI exemplified by steroids as model compounds. J Chrom B 1091 (2018) 67-78 (doi: 10.1016/j.jchromb.2018.05.017)

[O84]     Teubel J, Wüst B, Schipke C, Peters O, Parr MK. Methods in endogenous steroid profiling – a comparison of gas chromatography mass spectrometry (GC-MS) with supercritical fluid chromatography tandem mass spectrometry (SFC-MS/MS). J Chrom A 1554 (2018) 101-116 (doi:10.1016/j.chroma.2018.04.035)

[O83]     Keiler AM, Zierau O, Wolf S, Diel P, Schänzer W, Vollmer G, Machalz D, Wolber G, Parr MK. Androgen and estrogen receptor mediated activities of 4-hydroxytestosterone, 4-hydroxy­androstane­dione and their human metabolites in yeast based assays. Tox Letters 292 (2018) 39–45

[O82]     Montacir O, Montacir H, Springer A, Hinderlich S, Mahboudi F, Saadati A, Parr MK. Physicochemical characterization, glycosylation pattern and biosimilarity assessment of the fusion protein Etanercept. The Protein Journal 37 (2018) 164-179 (doi:10.1007/s10930-018-9757-y)

[O81]     Liu J, Chen L, Joseph JF, Naß A, Stoll A, de la Torre X, Botrè F, Wolber G, Parr MK, Bureik M. Combined chemical and biotechnological production of 20βOH-NorDHCMT, a long-term metabolite of Oral-Turinabol (DHCMT). J Inorg Biochem 183 (2018) 165-171 (doi: 10.1016/j.jinorgbio.2018.02.020)

[O80]     Assaf J, Gomes DZ, Wuest B, Parr MK. Photostability testing using online reactor HPLC hyphenation and mass spectrometric compound identification illustrated by ketoprofen as model compound. J Pharmaceut Biomed Anal 145 (2017) 414-422 (doi: 10.1016/j.jpba.2017.07.006)

[O79]     González-Rodríguez S, Quadir MA, Gupta S, Walker KA, Zhang X, Spahn V, Labuz D, Rodriguez-Gaztelumendi A, Schmelz M, Joseph J, Parr MK, Machelska H, Haag R, Stein C. Polyglycerol-opioid conjugate produces analgesia devoid of side effects. eLife eLife 6 (2017) e27081 (doi: 10.7554/eLife.27081)

[O78]     Montacir O, Montacir H, Eravci M, Springer A, Hinderlich S, Saadati A, Parr MK. Comparability study of rituximab originator and follow-on biopharmaceutical. J Pharmaceut Biomed 140 (2017) 239-251 (doi: 10.1016/j.jpba.2017.03.029)

[O77]     Parr MK, Blokland MH, Liebetrau F, Schmidt AH, Stanic M, Kwiatkowska D, Waraksa E, Sterk SS. Distinction of clenbuterol intake from drug or contaminated food of animal origin in a controlled administration trial – the potential of enantiomeric separation for doping control analysis. Food Add Contam A 34 (2017) 525-535 (doi: 10.1080/19440049.2016.1242169)

[O76]     Koehler K, Geyer H, Schultze G, Parr MK, Guddat S, Braun H, Mareck U, Thevis M, Schänzer W. Nutritional supplements: Still a risk of inadvertent doping? An extended international follow-up. Recent advances in doping analysis (20). Sportverlag Strauß, Köln (2017) 63-68

[O75]     Parr MK, Wuest B, Naegele E, Joseph JF, Wenzel M, Schmidt AH, Stanic M, de la Torre X, Botrè F. SFC-MS/MS as orthogonal technique for improved screening for polar analytes in anti-doping control. Anal Bioanal Chem 408 (2016) 6789-6797 (doi: 10.1007/s00216-016-9805-4)

[O74]     Krumbiegel F, Hastedt M, Westendorf L, Niebel A, Methling M, Parr MK, Tsokos M. The use of nails as an alternative matrix for the long-term detection of previous drug intake: validation of sensitive UHPLC-MS/MS methods for the quantification of 77 substances and comparison with of analytical results for drugs in nail and hair samples. Forensic Sci Med Pathol 12 (2016) 416-434 (doi: 10.1007/s12024-016-9801-1)

[O73]     Hengevoss J, Piechotta M, Müller D, Hanft F, Parr MK, Schänzer W, Diel P. Combined effects of androgen anabolic steroids and physical activity on the hypothalamic pituitary-gonadal axis. J Steroid Biochem Mol Biol 150 (2015) 86-96 (doi: 10.1016/j.jsbmb.2015.03.003)

[O72]     Empl MT, Kammeyer P, Ulrich R, Joseph JF,Parr MK, Ina Willenberg I, Schebb NH, Baumgärtner W, Röhrdanz E, Steffen C, Steinberg P. The influence of chronic L-carnitine supplementation on the formation of preneoplastic and atherosclerotic lesions in the colon and aorta of male F344 rats. Arch Toxicol 89 (2015) 2079-87 (doi:10.1007/s00204-014-1341-4)

[O71]     Parr MK, Botrè F, Naß A, Hengevoss J, Diel P, Wolber G. Ecdysteroids: A novel class of anabolic agents? Biol Sport 32 (2015) 169-173 (doi: 10.5604/20831862.1144420)

[O70]     de la Torre X, Colamonici C, Curcio D, Jardines D, Molaioni F, Parr MK, Botrè F. Detection of formestane abuse by mass spectrometric techniques. Drug Test Anal 6 (2014) 1133-40

[O69]     Parr MK, Zhao P, Haupt O, Ngueu ST, Hengevoss J, Fritzemeier KH, Piechotta M, Schlörer N, Muhn P, Zheng WY, Xie MY, Diel P. Estrogen receptor beta is involved in skeletal muscle hypertrophy induced by the phytoecdysteroid ecdysterone. Mol Nutr Food Res 58 (2014) 1861-1872 (doi: 10.1002/mnfr.201300806)

[O68]     Parr MK, Schänzer W, Schlörer NE, Voronina E, Hengevoss J, Diel P. Alternative detection strategies for anabolic steroid abuse by NMR metabonomics and endocrine feedback loop analyses. In: Schänzer W, Geyer H, Gotzmann A, Mareck U (eds). Recent advances in doping analysis (20). Sportverlag Strauß, Köln (2012) 46-51

[O67]     Parr MK, Daniels J, Schlörer N, Schänzer W. Structure proof of tibolone 3-hydroxy metabolite. In: Schänzer W, Geyer H, Gotzmann A, Mareck U (eds). Recent advances in doping analysis (20). Sportverlag Strauß, Köln (2012) 28-33

[O66]     Müller D, Opfermann G, Rojas Vega S, Schlörer N, Pokrywka A, Kwiatowska D, Diel P, Schänzer W, Parr MK. Analysis of steroid profile alteration, metabolite excretion and biological activity of 5α-androst-1-ene-3,17-dione. In: Schänzer W, Geyer H, Gotzmann A, Mareck U (eds). Recent advances in doping analysis (20). Sportverlag Strauß, Köln (2012) 197-200

[O65]     Bauer A, Rataj F, Zierau O, Anielski P, Große J, Parr MK, Vollmer G, Thieme D. Characterization of identity, metabolism and androgenic activity of 17-hydroxyandrosta-3,5-diene by GC-MS and a yeast transactivation system. Arch Toxicol 86 (2012) 1873-1884

[O64]     Parr MK, Zöllner A, Fußhöller G, Opfermann G, Schlörer N, Zorio M, Bureik M, Schänzer W. Unexpected contribution of cytochrome P450 enzymes CYP11B2 and CYP21, as well as CYP3A4 in xenobiotic androgen elimination - insights from metandienone metabolism. Tox Letters 213 (2012) 381-391

[O63]     Bredehöft M, Baginski R, Parr MK, Thevis M, Schänzer W. Investigations of the microbial transformation of cortisol to prednisolone in urine samples. J Steroid Biochem Mol Biol 129 (2012) 54–60

[O62]     Parr MK, Blatt C, Zierau O, Hess C, Gütschow M, Fußhöller G, Opfermann G, Schänzer W, Diel P. Endocrine characterization of the designer steroid methyl-1-testosterone - investigations on tissue specific anabolic-androgenic potency, side effects and metabolism. Endocrinology 152 (2011) 4718-28

[O61]     Parr MK, Pokrywka A, Kwiatkowska D, Schänzer W. Ingestion of designer supplements produced positive doping cases unexpected by the athletes. Biol Sport 28 (2011) 153-157

[O60]     Wolf S, Diel P, Parr MK, Rataj F, Schänzer W, Vollmer G, Zierau O. Detection of methyltestosterone abuse using a yeast transactivation system. Arch Toxicol 85 (2011) 285-292

[O59]     Parr MK, Opfermann G, Geyer H, Westphal F, Sönnichsen FD, Zapp J, Kwiatkowska D, Schänzer W. Seized designer supplement named “1-Androsterone”: Identification as 3β-hydroxy-5α-androst-1-en-17-one and its urinary elimination. Steroids 76 (2011) 540-547

[O58]     Parr MK, Fußhöller G, Schlörer N, Opfermann G, Geyer H, Rodchenkov G, Schänzer W. Detection of delta-6-methyltestosterone in a “dietary supplement” and GC-MS/MS investigations on its urinary metabolism. Tox Letters 201 (2011) 101-104

[O57]     Hülsemann F, Flenker U, Parr MK, Geyer H, Schänzer W. Authenticity control and identification of origin of synthetic creatine-monohydrate by isotope ratio mass spectrometry. Food Chem 125 (2011) 767-772

[O56]     Parr MK, Opfermann G, Schlörer N, Geyer H, Rataj F, Zierau O, Diel P, Schänzer W. Sense or nonsense of prohormone designing: Reduced metandienone as supplement. In: Schänzer W, Geyer H, Gotzmann A, Mareck U (eds). Recent advances in doping analysis (19). Sportverlag Strauß, Köln (2011) 15-23

[O55]     Orlovius AK, Guddat S, Parr MK, Koch A, Gütschow M, Thevis M, Schänzer W. Identification and monitoring of octopamine sulfoconjugate in urine by LC/(ESI)-MS/MS. In: Schänzer W, Geyer H, Gotzmann A, Mareck U (eds). Recent advances in doping analysis (19). Sportverlag Strauß, Köln (2011) 34-42

[O54]     Wolf S, Rataj F, Zierau O, Ostermann K, Diel P, Parr MK, Vollmer G, Rödel G. A novel combined approach to detect androgenic activities with yeast based assays in Schizosaccharomyces pombe and Saccharomyces cerevisiae. Tox Letters 199 (2010) 410-415

[O53]     Zöllner A, Parr MK, Dragan CA, Dräs S, Schlörer N, Peters FT, Maurer HH, Schänzer W, Bureik M. CYP21-catalyzed production of the long term urinary metandienone metabolite 17β-hydroxymethyl-17α-methyl-18-norandrosta-1,4,13-trien-3-one: A contribution to the fight against doping. Biol Chem 391 (2010) 119-127

[O52]     Parr MK, Diel P, Zierau O, Schänzer W. Investigations regarding the WADA classification of the supplement ingredient androsta-1,4,6-triene-3,17-dione. In: Schänzer W, Geyer H, Gotzmann A, Mareck U (eds). Recent advances in doping analysis (18). Sportverlag Strauß, Köln (2010) 34-41

[O51]     Parr MK, Fußhöller G, Gütschow M, Hess C, Schänzer W. GC-MS(/MS) investigations on long-term metabolites of 17-methyl steroids. In: Schänzer W, Geyer H, Gotzmann A, Mareck U (eds). Recent advances in doping analysis (18). Sportverlag Strauß, Köln (2010) 64-73

[O50]     Parr MK, Westphal F, Sönnichsen FD, Geyer H, Schänzer W. 1-DHEA identification in seized dietary supplement. In: Schänzer W, Geyer H, Gotzmann A, Mareck U (eds). Recent advances in doping analysis (18). Sportverlag Strauß, Köln (2010) 241-244

[O49]     Orlovius AK, Parr MK, Guddat S, Gütschow M, Thevis M, Schänzer W. Detection of urinary phase-I and phase-II metabolites of ephedrine and oxilofrine by LC-MS/MS. In: Schänzer W, Geyer H, Gotzmann A, Mareck U (eds). Recent advances in doping analysis (18). Sportverlag Strauß, Köln (2010) 152-155

[O48]     Parr MK, Zoellner A, Bureik M, Dragan CA, Schlörer N, Peters F, Maurer HH, Schänzer W. Production of metandienone longterm-metabolite using S. pombe based biotransformation assay. In: Schänzer W, Geyer H, Gotzmann A, Mareck U (eds). Recent advances in doping analysis (17). Sportverlag Strauß, Köln (2009) 95-96

[O47]     Parr MK, Haenelt N, Fußhöller G, Flenker U, Geyer H, Rodchenkov G, Opfermann G, Schänzer W. Recent steroid findings in “designer supplements”. In: Schänzer W, Geyer H, Gotzmann A, Mareck U (eds). Recent advances in doping analysis (17). Sportverlag Strauß, Köln (2009) 71-80

[O46]     Pozo OJ, Lootens L, Van Eenoo P, Deventer K, Meuleman P, Leroux-Roels G, Parr MK, Schänzer W, Delbeke FT. Combination of liquid-chromatography tandem mass spectrometry in different scan modes with human and chimeric mouse urine for the study of steroid metabolism. Drug Test Anal 1 (2009) 554-567

[O45]     Orlovius AK, Guddat S, Parr MK, Kohler M, Gütschow M, Thevis M, Schänzer W. Terbutaline sulfoconjugate: Characterisation and urinary excretion monitored by LC/ESI-MS/MS. Drug Test Anal 1 (2009) 568-575

[O44]     Brooker L, Parr MK, Cawley A, Flenker U, Howe C, Kazlauskas R, Schänzer W, George A. Development of criteria for the detection of adrenosterone administration by gas chromatography-mass spectrometry and gas chromatography-combustion-isotope ratio mass spectrometry for doping control. Drug Test Anal 1 (2009) 587-595

[O43]     Pozo OJ, Van Eenoo P, Deventer K, Lootens L, Van Thuyne W, Parr MK, Schänzer W, Sancho JV, Hernández F, Meuleman P, Leroux-Roels G, Delbeke FT. Detection and characterization of a new metabolite of 17alpha-methyltestosterone. Drug Metab Dispos 37 (2009) 2153-62

[O42]     Parr MK, Laudenbach-Leschowsky U, Höfer N, Schänzer W, Diel P. Anabolic and androgenic activity of 19-norandrostenedione after oral and subcutaneous administration - analysis of side effects and metabolism. Tox Letters 188 (2009) 137–141

[O41]     Parr MK, Fußhöller G, Schlörer N, Opfermann G, Piper T, Rodchenkov G, Schänzer W. Metabolism of androsta-1,4,6-triene-3,17-dione and detection by gas chromatogrphy/mass spectrometry in doping control. Rapid Commun Mass Spectrom 23 (2009) 207-218

[O40]     Parr MK, Gütschow M, Daniels J, Opfermann G, Thevis M, Schänzer W. Identification of steroid isoxazole isomers marketed as designer supplement. Steroids 74 (2009) 322-328

[O39]     Köhler K, Parr MK, Geyer H, Mester J, Schänzer W. Serum testosterone and urinary excretion of steroid hormone metabolites after administration of a high-dose zinc supplement. Eur J Clin Nutr 63 (2009) 65-70

[O38]     Parr MK, Köhler K, Geyer H, Guddat S, Schänzer W. Clenbuterol marketed as dietary supplement. Biomed Chromatogr 22 (2008) 298-300

[O37]     Parr MK, Kazlauskas R, Schlörer N, Opfermann G, Piper T, Schulze G, Schänzer W. 6α-Methylandrostenedione: Gas chromatographic mass spectrometric detection in doping control. Rapid Commun Mass Spectrom 22 (2008) 321-329

[O36]     Parr MK, Geyer H, Gütschow M, Haenelt N, Opfermann G, Thevis M, Schänzer W. New steroids on the "supplement" market. In: Schänzer W, Geyer H, Gotzmann A, Mareck U (eds). Recent advances in doping analysis (16). Sportverlag Strauß, Köln (2008) 73-82

[O35]     Parr MK, Zapp J, Becker M, Opfermann G, Bartz U, Schänzer W. Steroidal isomers with uniform mass spectra of their per-TMS derivatives: Synthesis of 17-hydroxyandrostan-3-ones, androst-1-, and -4-ene-3,17-diols. Steroids 72 (2007) 545-551

[O34]     Parr MK, Geyer H, Hoffmann B, Köhler K, Mareck U, Schänzer W. High amounts of 17-methylated anabolic-androgenic steroids in effervescent tablets on the dietary supplement market. Biomed Chromatogr 21 (2007) 164-168

[O33]     Kohler M, Parr MK, Opfermann G, Thevis M, Schlörer N, Marner FJ, Schänzer W. Metabolism of 4-hydroxyandrostenedione and 4-hydroxytestosterone: Mass spectrometric identification of urinary metabolites. Steroids 72 (2007) 278-286

[O32]     Parr MK, Opfermann G, Piper T, Schänzer W. Characterisation of steroid metabolites recently detected in doping control analyses. In: Schänzer W, Geyer H, Gotzmann A, Mareck U (eds). Recent advances in doping analysis (15). Sportverlag Strauß, Köln (2007) 143-152

[O31]     Parr MK, Orlovius A, Guddat S, Gütschow M, Thevis M, Schänzer W. Sulfoconjugates of heavy volatile nitrogen containing doping substances utilizing LC-MS/MS. In: Schänzer W, Geyer H, Gotzmann A, Mareck U (eds). Recent advances in doping analysis (15). Sportverlag Strauß, Köln (2007) 97-102

[O30]     Mareck U, Haenelt N, Parr MK, Geyer H, Guddat S, Thevis M, Schänzer W. Direct quantification of salbutamol in human urine by means of LC-MS/MS. In: Schänzer W, Geyer H, Gotzmann A, Mareck U (eds). Recent advances in doping analysis (15). Sportverlag Strauß, Köln (2007) 87-96

[O29]     Köhler K, Geyer H, Guddat S, Orlovius A, Parr MK, Thevis M, Mester J, Schänzer W. Sibutramine found in chinese herbal slimming tea and capsules. In: Schänzer W, Geyer H, Gotzmann A, Mareck U (eds). Recent advances in doping analysis (15). Sportverlag Strauß, Köln (2007) 367-370

[O28]     Schänzer W, Geyer H, Fußhöller G, Halatcheva N, Kohler M, Parr MK, Guddat S, Thomas A, Thevis M. Mass spectrometric identification and characterization of a new long-term metabolite of metandienone. Rapid Commun Mass Spectrom 10 (2006) 2252-2258

[O27]     Geyer H, Mareck U, Köhler K, Parr MK, Schänzer W. Cross-contaminations of vitamin- and mineral-tablets with metandienone and stanozolol. In: Schänzer W, Geyer H, Gotzmann A, Mareck U (eds). Recent advances in doping analysis (14). Sport und Buch Strauß, Köln (2006) 11-16

[O26]     Opfermann G, Kohler M, Fußhöller G, Parr MK, Sigmund G, Schänzer W. Comparison of uncertainties: the standard deviations of the method of two calibration curves with different preparatory steps. In: Schänzer W, Geyer H, Gotzmann A, Mareck U (eds). Recent advances in doping analysis (14). Sport und Buch Strauß, Köln (2006) 489-492

[O25]     Köhler K, Parr MK, Geyer H, Bode C, Schänzer W. Serum testosterone and urinary steroid profiles after administration of a zinc supplement. In: Schänzer W, Geyer H, Gotzmann A, Mareck U (eds). Recent advances in doping analysis (14). Sport und Buch Strauß, Köln (2006) 403-406

[O24]     Kohler M, Parr MK, Opfermann G, Schänzer W. Metabolism of 4-hydroxyandrostenedione and 4-hydroxytestosterone. In: Schänzer W, Geyer H, Gotzmann A, Mareck U (eds). Recent advances in doping analysis (14). Sport und Buch Strauß, Köln (2006) 169-179

[O23]     Schänzer W, Geyer H, Fußhöller G, Halatcheva N, Kohler M, Parr MK, Guddat S, Thomas A, Thevis M. Mass spectrometric identification and characterization of a new long-term metabolite of metandienone. In: Schänzer W, Geyer H, Gotzmann A, Mareck U (eds). Recent advances in doping analysis (14). Sport und Buch Strauß, Köln (2006) 217-218

[O22]     Parr MK, Opfermann G, Schänzer W. Detection of new 17-alkylated anabolic steroids on WADA 2006 list. In: Schänzer W, Geyer H, Gotzmann A, Mareck U (eds). Recent advances in doping analysis (14). Sport und Buch Strauß, Köln (2006) 249-258

[O21]     Parr MK, Fusshöller G, Opfermann G, Kohler M, Hebestreit M, Schänzer W. Synthesis of reference compounds for the identification of metabolites of 4-hydroxy¬testosterone. In: Schänzer W, Geyer H, Gotzmann A, Mareck U (eds). Recent advances in doping analysis (13). Sport und Buch Strauß, Köln (2005) 65-74

[O20]     Parr MK, Opfermann G, Schänzer W. Analytical properties of 4-hydroxysteroids and some esters. In: Schänzer W, Geyer H, Gotzmann A, Mareck U (eds). Recent advances in doping analysis (12). Sport und Buch Strauß, Köln (2004) 129-139

[O19]     Parr M, Geyer H, Opfermann G, Schänzer W. Prescription drugs and new anabolic steroids in nutritional supplements. In: Schänzer W, Geyer H, Gotzmann A, Mareck U (eds). Recent advances in doping analysis (12). Sport und Buch Strauß, Köln (2004) 71-80

[O18]     Geyer H, Gülker A, Mareck U, Parr MK, Schänzer W. Some good news from the field of nutritional supplements. In: Schänzer W, Geyer H, Gotzmann A, Mareck U (eds). Recent advances in doping analysis (12). Sport und Buch Strauß, Köln (2004) 91-97

[O17]     Parr MK, Geyer H, Sigmund G, Köhler K, Schänzer W. Screening of nutritional supplements for stimulants and other drugs. In: Schänzer W, Geyer H, Gotzmann A, Mareck U (eds). Recent advances in doping analysis (11). Sport und Buch Strauß, Köln (2003) 67-75

[O16]     Parr MK, Geyer H, Reinhart U, Schänzer W. Analytical strategies for the detection of non-labelled anabolic androgenic steroids in nutritional supplements. Food Addit Contam 21 (2004) 632-640

[O15]     Machnik M, Due M, Parr M, von Kuk C, Schänzer W. Case study: Doping substances in equestrian food supplements. Chromatographia 59 (2004) S131-S135

[O14]     Geyer H, Parr MK, Mareck U, Reinhart U, Schrader Y, Schänzer W. Analysis of non-hormonal nutritional supplements for anabolic-androgenic steroids - results of an international study. Int J Sport Med 25 (2004) 124-129

[O13]     Mahler N, Geyer H, Parr M, Kamber M. Untersuchung von Nahrungsergänzungsmitteln des Schweizer Marktes. Schweizerische Zeitschrift für Sportmedizin und Sporttraumatologie 3 (2004) 133

[O12]     Machnik M, Due M, Parr MK, Schänzer W. Anabole Steroide in pflanzlichen Arzneimitteln für Pferde. Pferdeheilkunde 19 (2003) 155-158

[O11]     Geyer H, Bredehöft M, Mareck U, Parr M, Schänzer W. High doses of the anabolic steroid metandienone found in dietary supplements. Eur J Sport Sci 3 (2003) 1

[O10]     Parr MK, Geyer H, Gülker A, Mareck U, Schänzer W. Nahrungsergänzungsmittel-Alternativen mit geringem Dopingrisiko. Leistungssport 6 (2003) 31-32

[O9]       Machnik M, Düe M, Parr MK, Schänzer W. Anabolic steroids in plant medicines for horses. In: Schänzer W, Geyer H, Gotzmann A, Mareck U (eds). Recent advances in doping analysis (11). Sport und Buch Strauß, Köln (2003) 85-90

[O8]       Geyer H, Bredehöft M, Mareck U, Parr MK, Reinhart U, Schänzer W. Oxandrolone and high doses of metandienone found in nutritional supplements. In: Schänzer W, Geyer H, Gotzmann A, Mareck U (eds). Recent advances in doping analysis (11). Sport und Buch Strauß, Köln (2003) 77-84

[O7]       Parr MK, Geyer H, Reinhart U, Schänzer W. Approaches towards an improved analysis of nutritional supplements for anabolic androgenic steroids. In: Schänzer W, Geyer H, Gotzmann A, Mareck U (eds). Recent advances in doping analysis (10). Sport und Buch Strauß, Köln (2002) 87-96

[O6]       Geyer H, Parr MK, Reinhart U, Schrader Y, Mareck U, Schänzer W. Analysis of non-hormonal nutritional supplements for anabolic androgenic steroids - an international study. In: Schänzer W, Geyer H, Gotzmann A, Mareck U (eds). Recent advances in doping analysis (10). Sport und Buch Strauß, Köln (2002) 83-85

[O5]       Geyer H, Bredehöft M, Mareck U, Parr M, Schänzer W. Hohe Dosen des Anabolikums Metandienon in Nahrungsergänzungsmitteln gefunden. Deutsche Apotheker Zeitung 142 (2002) 50

[O4]       Henze MK, Opfermann G, Spahn-Langguth H, Schänzer W. Screening of beta-2 agonists and confirmation of fenoterol, orciprenaline, reproterol and terbutaline with gas chromatography-mass spectrometry as tetrahydroisoquinoline derivatives. J Chromatogr B 751 (2001) 93-105

[O3]       Henze MK, Spahn-Langguth H, Schänzer W. Reactions of salbutamol and reproterol with urine matrix components - preliminary results. In: Schänzer W, Geyer H, Gotzmann A, Mareck-Engelke U (eds). Recent advances in doping analysis (9). Sport und Buch Strauß, Köln (2001) 29-34

[O2]       Henze MK, Opfermann G, Spahn-Langhuth H, Schänzer W. Screening of beta-2-agonists and confirmation of fenoterol, reproterol, orciprenaline and terbutaline after cyclisation with formaldehyde. In: Schänzer W, Geyer H, Gotzmann A, Mareck-Engelke U (eds). Recent advances in doping analysis (8). Sport und Buch Strauß, Köln (2000) 59-68

[O1]       Henze MK, Opfermann G, Schänzer W. Liquid-liquid extraction-pH profiles of selected beta-2-sympathomimetic agonists. In: Schänzer W, Geyer H, Gotzmann A, Mareck-Engelke U (eds). Recent advances in doping analysis (7). Sport und Buch Strauß, Köln (1999) 335-340