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Alternative adaptive immunity in invertebrates

Kurtz J, Armitage SAO – 2006

Vertebrate adaptive immunity is characterized by challenge-specific long-term protection. This specific memory is achieved through the vast diversity of somatically rearranged immunological receptors such as antibodies. Whether or not invertebrates are capable of a comparable phenotypic plasticity and memory has long been a matter of debate. A recent study on Anopheles gambiae mosquitoes now establishes Down syndrome cell adhesion molecule (Dscam) as a key immune surveillance factor with characteristics analogous to antibodies.

Title
Alternative adaptive immunity in invertebrates
Author
Kurtz J, Armitage SAO
Publisher
Elsevier Science Ltd.,
Date
2006-11
Identifier
doi: 10.1016/j.it.2006.09.001
Appeared in
Trends in Immunology, 27(11): 493-6
Language
eng
Type
Text
Rights
© 2006 Elsevier Ltd. Published by Elsevier Inc. All rights reserved.