Office hours: Monday 12 - 13h.
Please Email or call Karin Hesse to make an appointment.
We are addressing the fundamental question how alternative splicing regulates cellular function and identity; our main model systems are the mammalian circadian clock as well as T cell activation and differentiation. Another focus of the lab are mechanisms that form the basis for signal-induced and cell type specific alternative splicing. We are employing a variety of techniques ranging from RNA-protein interaction assay and in vitro splicing to cell culture and mouse models.