Department of Biology, Chemistry, Pharmacy
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Projects GRK 1582
Scientific program
The scientific program is subdivided into four sections headed by one of the principal investigators. The scientific projects range from synthesis to spectroscopic characterization and theoretical description of currently poorly understood elemental fluorides and their use as oxidative agents (area A), to the application of complex elemental fluorides fort he synthesis of novel materials and fluorinated supports (area B). In addition, the development of innovative synthesis concepts and catalytic processes for the preparation of fluorinated organic compounds (area C) is pursued. Finally, the application of these concepts for the synthesis of novel building blocks with biological activity have advantageous pharmaceutical properties are in the focus of (area D). The intense collaborations between the different projects and interdisciplinary nature of them leads to a strong interlink between the different areas.
Area A - Metal Fluorides - Head: Prof. Dr. K. Seppelt (FU) |
|
| Project | Group |
|---|---|
| Spectroscopy of gaseous metal fluorides | Rühl |
| Oxidations using metal hexafluorides | Seppelt |
| Technetium(I)-Technetium(IV) fluorides | Abram |
| Low oxidation state fluorides | Seppelt |
Area B - Functional Materials - Head: Prof. Dr. E. Kemnitz (HU) |
|
| Project | Group |
| Metastable fluoride phases as catalysts | Kemnitz |
| Coatings based on nanoscopic metal fluorides | Kemnitz |
| Ab initio investigations of Cu, Ag and Au fluorides | Paulus |
| Supramolecular interactions based on the "fluorous effect" | Haag |
Area C - Catalytic Syntheses - Head: Prof. Dr. T. Braun (HU) |
|
| Project | Group |
| Fluorocomplexes of Rh and Pd | Braun |
| Catalytic C-F activation | Braun |
| Catalytic dehydrofluoration of fluorinated allenes | Lentz |
| Enantiselective syntheses of fluorinated carbonic acids | Czekelius |
Area D - Biologically active compounds - Head: Prof. Dr. B. Koksch (FU) |
|
| Project | Group |
| Cytotoxic fluorinated metal complexes | Gust |
| Fluorinated peptidic HIV-fusion inhibitors | Koksch |
| F-mediated H-bonds in peptides | Koksch |
| Fluorinated heterocycles | Reissig |
Detailed information concerning the sub-projects are available in german only.
