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New Paper in Organic Chemistry Frontiers

In our latest paper published in Organic Chemistry Frontiers, we introduce BT-SeCF2H as the first nucleophilic reagent for introducing the SeCF2H group onto organic molecules. The study of this group as a constituent moiety in pharmaceuticals and agrochemicals has been limited by the lack of methods to synthesise it with previous routes involving either indirect approaches or electrophilic difluoromethylselenylating reagents. BT-SeCF2H, on the other hand, allows for direct nucleophilic difluoromethylselenylation of readily available carboxylic acids and benzylic alcohols. 

Congratulations to the first author Matteo and to Stefan! The full text can be read here:

https://pubs.rsc.org/en/content/articlelanding/2021/qo/d1qo01104a  

News from Aug 25, 2021

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