An electrostatically assembled two-layer polymer coating imparts self-disinfecting, virucidal properties to surfaces via a catch-and-kill mechanism.

Detailed Explanation

The coating arrangement uses a positively charged first polymer layer for substrate adhesion, followed by a negatively charged second layer of alkylated polyglycerol sulfate for virus binding and disruption. Hydrophobic alkyl chains in the second layer disrupt viral envelopes, rendering pathogens inert. Layer-by-layer batch and continuous industrial dip-coating processes enable application to rigid and flexible substrates. Demonstrated virucidal efficacy exceeds 99.9% removal on cellulose acetate and air filter materials. Scalable manufacturing supports PPE and HVAC filter production. The assembly is adaptable to diverse substrates, including metals, glass, and polymers.

Key Innovation Features and Advantages

• Electrostatic layer-by-layer assembly ensures a robust bilayer structure without covalent crosslinking.
• Alkylated polyglycerol sulfate second layer delivers irreversible virucidal activity via envelope disruption.
• Versatile coating processes (discontinuous and continuous) enable scalable industrial applications on various substrates.

Use Cases

• Virucidal air filters and protective facemasks for healthcare and public transportation.
• Self-disinfecting high-touch surfaces in hospitals, schools, and offices.
• Durable antiviral coatings for HVAC systems in commercial buildings.

Commercial Opportunities

• Licensing coating technology to PPE and filter manufacturers.
• Development of long-lasting surface disinfectant products.
• Partnerships in the building maintenance and facility management sectors.

Current Status

Patent EP4036176A1 has been filed, with in vitro and surface-based virucidal efficacy demonstrated. Scale-up via LbL and continuous dip-coating processes is validated.