Organic Chemistry: Theranostic Macromolecular Prodrugs
M. Sc. Harald Rune Krüger received his master degree in chemistry at the Freie Universität Berlin (Germany) in 2011. In the same year he started his Phd studies under the supervision of Prof. M. Calderón and Prof. R. Haag. His research is focused on the synthesis and biochemical evaluation of polyglycerol based polymer therapeutics.
Dendritic polymer imaging systems for the evaluation of conjugate uptake and cleavage
H. R. Krüger, G. Nagel, S. Wedepohl, M. Calderón*. Manuscript submitted.
Imaging of Doxorubicin Release from Theranostic Macromolecular Prodrugs via Fluorescence Resonance Energy Transfer. H.R. Krüger, I. Schütz, A. Justies, K. Licha, P. Welker, V. Haucke, M. Calderón*. Journal of Controlled Release. Manuscript accepted.
Targeted delivery of dendritic polyglycerol-doxorubicin conjugates by scFv-SNAP fusion protein suppresses EGFR+ cancer cell growth. A. Hussain§, H.R. Krüger§, F. Kampmeier, T. Weissbach, K. Licha, F. Kratz, R. Haag, M. Calderón*, S. Barth*. Biomacromolecules (2013), 14, 2510–2520. § These author contributed equally