Carbon-based cores with polyglycerol shells - the importance of core flexibility for encapsulation of hydrophobic guests
"Lukowiak, M. C.; Ziem, B.; Achazi, K.; Gunkel-Grabole, G.; Popeney, C. S.; Thota, B. N. S.; Bottcher, C.; Krueger, A.; Guan, Z.; Haag, R." – 2015
Two core-shell nanoparticles with polyglycerol shells and sp(3) carbon cores with different flexibilities (soft dendritic polyethylene and hard nanodiamond) were synthesized, their encapsulation capacities were compared, and their ability to transport into tumor cells was investigated. The nanocarrier with a soft core was superior to the hard one.
Title
Carbon-based cores with polyglycerol shells - the importance of core flexibility for encapsulation of hydrophobic guests
Author
"Lukowiak, M. C.; Ziem, B.; Achazi, K.; Gunkel-Grabole, G.; Popeney, C. S.; Thota, B. N. S.; Bottcher, C.; Krueger, A.; Guan, Z.; Haag, R."
Publisher
Journal of Materials Chemistry B
Keywords
"agents; architectures; chain-walking; drug-delivery systems; nanocarriers; nanoparticles; polymer therapeutics; release; solubilization; unimolecular micelles"
Date
2015
Identifier
2050-7518 (Electronic) 2050-750X (Linking)
Source(s)
Type
Text