Supramolecular hydrophobic guest transport system based on pillar[5]arene
"Qi, Z.; Achazi, K.; Haag, R.; Dong, S.; Schalley, C. A." – 2015
A pillar[5]arene-based bioactive guest loading system has been developed, which can increase the solubility of the drug norharmane in aqueous medium, and also enable its pH-stimulated release. Furthermore, this supramolecular transport system reduces the toxicity of loaded guest.
Title
Supramolecular hydrophobic guest transport system based on pillar[5]arene
Author
"Qi, Z.; Achazi, K.; Haag, R.; Dong, S.; Schalley, C. A."
Publisher
Chem Commun (Camb)
Keywords
"Carbolines/*chemistry/toxicity; Drug Carriers/*chemistry; HEK293 Cells; Hep G2 Cells; Humans; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Macrocyclic Compounds/*chemistry; Monocytes; Proton Magnetic Resonance Spectroscopy; Solubility; Spectrometry, Fluorescence"
Date
2015
Identifier
1364-548X (Electronic) 1359-7345 (Linking)
Source(s)
Type
Text