Springe direkt zu Inhalt

M.Sc. Paul- Lennard Mendez

Paul completed his Master of Science in medical biotechnology at the Technische Universität Berlin in September 2019. He received a scholarship from the International Max-Planck Research School for Biology AND Computation (IMPRS-BAC) and joined the Knaus Lab in October 2019. His research has a strong focus on mechanotransduction and mechanically induced genetic changes in the vascular system.

pmendez

Biochemistry

PhD Candidate

Signal Transduction

Email
pmendez (at) zedat.fu-berlin.de

Biochemisches Blockpraktikum- Lipide und Membranen

Method Module: Growth Factor Signaling and Interplay with Cell Mechanics

Mendez PL, Obendorf L, Jatzlau J, Burdzinski W, Reichenbach M, Nageswaran V, Haghikia A, Stangl V, Hiepen C, Knaus P. Atheroprone fluid shear stress-regulated ALK1-Endoglin-SMAD signaling originates from early endosomes. BMC Biol. 2022 Sep 28. DOI: 10.1186/s12915-022-01396-y.

Mendez, P. L., Obendorf, L., Knaus, P. Visualization and Quantification of TGFβ/BMP/SMAD Signaling under Different Fluid Shear Stress Conditions using Proximity-Ligation-Assay. J. Vis. Exp. (175)

Reichenbach, M.; Mendez, P.-L.; da Silva Madaleno, C.; Ugorets, V.; Rikeit, P.; Boerno, S.; Jatzlau, J.; Knaus, P. Differential Impact of Fluid Shear Stress and YAP/TAZ on BMP/TGF‐β Induced Osteogenic Target Genes. Advanced Biology 2021

Hiepen, C.; Mendez, P.-L.; Knaus, P. It Takes Two to Tango: Endothelial TGFβ/BMP Signaling Crosstalk with Mechanobiology. Cells 2020.