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Publications

  1. Absmeier E*, Chandrasekaran V*, O´Reilly FJ, Stowell JAW, Rappsilber J, Passmore LA (2023) Specific recognition and ubiquitination of translating ribosomes by mammalian CCR4-NOT. Nature Structural & Molecular Biology 30(9):1314-1322, DOI: 10.1038/s41594-023-01075-8
  2. Höpfler M, Absmeier E, Peak-Chew SY, Vartholomaiou E, Passmore LA, Gasic I, Hegde RS (2023) Mechanism of ribosome-associated mRNA degradation during tubulin autoregulation. Molecular Cell, 83(13):2290-2302.e13, DOI:10.1016/j.molcel.2023.05.020
  3. Absmeier E*, Vester K*, Ghane T, Burakovskiy D, Milon P, Imhof P, Rodnina MV, Santos KF*, Wahl MC (2021) Long-range allostery mediates cooperative adenine nucleotide binding by the Ski2-like RNA helicase Brr2. J Biol Chem, 297., DOI: 10.1016/j.jbc.2021.100829
  4. Jia J, Absmeier E, Holton N, Pietrzyk-Brzezinska AJ, Hackert P, Bohnsack KE, Bohnsack MT, Wahl MC (2020) The interaction of DNA repair factors ASCC2 and ASCC3 is affected by somatic cancer mutations. Nature Communications, 11, 5535., DOI: 10.1038/s41467-020-19221-x
  5. Jia J, Ganichkin OM, Preußner M, Absmeier E, Alings C, Loll B, Heyd F, Wahl MC (2020) A Snu114–GTP–Prp8 module forms a relay station for efficient splicing in yeast. Nucleic Acid Research, 48, 4572-4584.,
  6. DOI: 10.1093/nar/gkaa182
  7. Absmeier E*,#, Santos KF*, Wahl MC (2020) Molecular Mechanism Underlying Inhibition of Intrinsic ATPase Activity in a Ski2-like RNA Helicase. Structure, 28, 236-243., DOI: 10.1016/j.str.2019.11.014
  8. Pietrzyk-Brzezinska AJ, Absmeier E, Klauck E, Wen Y, Antelmann H, Wahl MC (2018) Crystal Structure of the Escherichia coli DExH-Box NTPase HrpB. Structure 26, 1462-1473., DOI: 10.1016/j.str.2018.07.013
  9. Absmeier E, Becke C, Wollenhaupt J, Santos KF, Wahl MC (2017) Interplay of cis- and trans-regulatory mechanisms in the spliceosomal RNA helicase Brr2. Cell Cycle16, 100-112., DOI: 10.1080/15384101.2016.1255384
  10. Absmeier E, Wollenhaupt J, Mozaffari-Jovin S, Becke C, Lee CT, Preussner M, Heyd F, Urlaub H, Lührmann R, Santos KF, Wahl MC (2015) The large N-terminal region of the Brr2 RNA helicase guides productive spliceosome activation. Genes & Development 29, 2576-2587. Cover story, DOI: 10.1101/gad.271528.115
  11. Absmeier E, Rosenberger L, Apelt L, Becke C, Santos KF, Stelzl U, Wahl MC (2015) A non-canonical PWI domain in the N-terminal helicase-associated region of the spliceosomal Brr2 protein. Acta Crystallogr D 71, 762-771., DOI: 10.1107/S1399004715001005

*equal contribution, #co-corresponding