Springe direkt zu Inhalt

Multicompartment micelles from silicone-based triphilic block copolymers

J.-N. Marsat, F. Stahlhut, A. Laschewsky, H. von Berlepsch and C. Böttcher – 2013

An amphiphilic linear ternary block copolymer was synthesised in three consecutive steps via reversible addition-fragmentation chain transfer polymerisation. Oligo(ethylene glycol) monomethyl ether acrylate was engaged as a hydrophilic building block, while benzyl acrylate and 3-tris(trimethylsiloxy)silyl propyl acrylate served as hydrophobic building blocks. The resulting "triphilic" copolymer consists thus of a hydrophilic (A) and two mutually incompatible "soft" hydrophobic blocks, namely, a lipophilic (B) and a silicone-based (C) block, with all blocks having glass transition temperatures well below 0 A degrees C. The triphilic copolymer self-assembles into spherical multicompartment micellar aggregates in aqueous solution, where the two hydrophobic blocks undergo local phase separation into various ultrastructures as evidenced by cryogenic transmission electron microscopy. Thus, a silicone-based polymer block can replace the hitherto typically employed fluorocarbon-based hydrophobic blocks in triphilic block copolymers for inducing multicompartmentalisation.

Titel
Multicompartment micelles from silicone-based triphilic block copolymers
Verfasser
J.-N. Marsat, F. Stahlhut, A. Laschewsky, H. von Berlepsch and C. Böttcher
Datum
2013
Kennung
DOI: 10.1007/s00396-013-3001-2
Zitierweise
Colloid. Polym. Sci. 2013, 291, 2561 - 2567
Sprache
eng
Art
Text