bildstreifen

Dr. Jérémie Mortier

jeremie_150x150

Institut für Pharmazie

Postdoctoral researcher

Aufgabenbereich

Molecular dynamics studies of polypeptides, development of novel Arginase inhibitors

Adresse Freie Universität Berlin
Institut für Pharmazie
Königin-Luisestr. 2+4
Raum 277
14195 Berlin
Telefon +49 30 838 58090
Fax +49 30 545 4 52686
E-Mail jeremie.mortier@fu-berlin.de
Titel/Autor     Jahr
Inhibitory potency of flavonoid derivatives on influenza virus neuraminidase
C Rakers, SM Schwerdtfeger, J Mortier, S Duwe, T Wolff, G Wolber, ...
Bioorganic & Medicinal Chemistry Letters
    2014
Discovery of Sanggenon G as a natural cell-permeable small-molecular weight inhibitor of X-linked inhibitor of apoptosis protein (XIAP)
MA Seiter, S Salcher, M Rupp, J Hagenbuchner, U Kiechl-Kohlendorfer, ...
FEBS Open Bio
    2014
Synthesis, Biological Evaluation, and Docking Studies of New 2‐Furylbenzimidazoles as Anti‐Angiogenic Agents: Part II
A Temirak, YM Shaker, FAF Ragab, MM Ali, SM Soliman, J Mortier, ...
Archiv der Pharmazie 347 (4), 291-304
    2014
Balancing selectivity vs stability using molecular dynamics and umbrella sampling
J Mortier, EK Nyakatura, M Miettinen, C Baldauf, G Wolber, B Koksch
Journal of cheminformatics 6 (Suppl 1), O22
    2014
An Unusual Interstrand H-Bond Stabilizes the Heteroassembly of Helical αβγ-Chimeras with Natural Peptides
EK Nyakatura, R Rezaei Araghi, J Mortier, S Wieczorek, C Baldauf, ...
ACS chemical biology 9 (3), 613-616
    2014
Synthesis, biological activity and structure–activity relationships of new benzoic acid-based protein tyrosine phosphatase inhibitors endowed with insulinomimetic effects in mouse C2C12 skeletal muscle cells
R Ottanà, R Maccari, J Mortier, A Caselli, S Amuso, G Camici, A Rotondo, ...
European journal of medicinal chemistry 71, 112-127
    2014
Design, synthesis and structure–activity relationship of novel quinoxaline derivatives as cancer chemopreventive agent by inhibition of tyrosine kinase receptor
SA Galal, AS Abdelsamie, SM Soliman, J Mortier, G Wolber, MM Ali, ...
European journal of medicinal chemistry 69, 115-124
    2013
Impact of fluorination on proteolytic stability of peptides in human blood plasma
V Asante, J Mortier, H Schlüter, B Koksch
Bioorganic & medicinal chemistry 21 (12), 3542-3546
    2013
Design, synthesis, inhibition studies, and molecular modeling of pepstatin analogues addressing different secreted aspartic proteinases of< i> Candida albicans</i>
CD Cadicamo, J Mortier, G Wolber, M Hell, IE Heinrich, D Michel, ...
Biochemical pharmacology 85 (7), 881-887
    2013
< i> In silico</i> virtual screening approaches for anti-viral drug discovery
MS Murgueitio, M Bermudez, J Mortier, G Wolber
Drug Discovery Today: Technologies 9 (3), e219-e225
3   2012
Computational tools for in silico fragment-based drug design
J Mortier, C Rakers, R Frederick, G Wolber
Current topics in medicinal chemistry 12 (17), 1935-1943
7   2012
A Simple Synthesis of D-Galactono-1, 4-Lactone and Key Building Blocks for the Preparation of Galactofuranosides
VL de Talancé, E Thiery, G Eppe, SE Bkassiny, J Mortier, SP Vincent
Journal of Carbohydrate Chemistry 30 (7-9), 605-617
2   2011
Anti-virulence strategy against Brucella suis: synthesis, biological evaluation and molecular modeling of selective histidinol dehydrogenase inhibitors
MR Abdo, P Joseph, J Mortier, F Turtaut, JL Montero, B Masereel, ...
Organic & biomolecular chemistry 9 (10), 3681-3690
4   2011
NF-κB inducing kinase (NIK) inhibitors: identification of new scaffolds using virtual screening
J Mortier, B Masereel, C Remouchamps, C Ganeff, J Piette
Bioorganic & medicinal chemistry letters 20 (15), 4515-4520
17   2010
Pyrazolo [4, 3-c] isoquinolines as potential inhibitors of NF-κB activation
J Mortier, R Frederick, C Ganeff, C Remouchamps, P Talaga, L Pochet, ...
Biochemical pharmacology 79 (10), 1462-1472
11   2010