rhs_col

Originalarbeiten

Pfalzgraff A, Heinbockel L, Su Q, Brandenburg K, Weindl G (2017) Synthetic anti-endotoxin peptides inhibit cytoplasmic LPS-mediated responses. Biochem Pharmacol. DOI: 10.1016/j.bcp.2017.05.015

Su Q, Pfalzgraff A, Weindl G (2017) Cell type-specific regulatory effects of glucocorticoids on cutaneous TLR2 expression and signalling. J Steroid Biochem Mol Biol. DOI: 10.1016/j.jsbmb.2017.03.023

Grohmann L, Becker D, Rademann J, Ma N, Schäfer-Korting M, Weindl G (2017) Biotransformation of 2,4-toluenediamine in human skin and reconstructed tissues. Arch Toxicol. DOI: 10.1007/s00204-017-1954-5

Su Q, Grabowski M, Weindl G (2017) Recognition of Propionibacterium acnes by human TLR2 heterodimers. Int J Med Microbiol 307: 108-12. DOI: 10.1016/j.ijmm.2016.12.002

Pfalzgraff A, Heinbockel L, Su Q, Gutsmann T, Brandenburg K, Weindl G (2016) Synthetic antimicrobial and LPS-neutralising peptides suppress inflammatory and immune responses in skin cells and promote keratinocyte migration. Sci Rep 6: 31577. DOI: 10.1038/srep31577

Bock S, Pfalzgraff A, Weindl G (2016) Sphingosine 1-phospate differentially modulates maturation and function of human Langerhans-like cells. J Dermatol Sci 82: 9-17. DOI: 10.1016/j.jdermsci.2016.01.002

Bock S, Murgueitio MS, Wolber G, Weindl G (2016) Acute myeloid leukaemia-derived Langerhans-like cells enhance Th1 polarization upon TLR2 engagement. Pharmacol Res 105: 44-53. DOI: 10.1016/j.phrs.2016.01.016

Klionsky DJ, ..., Weindl G, ..., Zughaier SM (2016) Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy 12: 1-222. DOI: 10.1080/15548627.2015.1100356

Guenova E, Skabytska Y, Hoetzenecker W, Weindl G, Sauer K, Tham M, Kim KW, Park JH, Seo JH, Ignatova D, Cozzio A, Levesque MP, Volz T, Köberle M, Kaesler S, Thomas P, Mailhammer R, Ghoreschi K, Schäkel K, Amarov B, Eichner M, Schaller M, Clark RA, Röcken M, Biedermann T (2015) IL-4 abrogates TH17 cell-mediated inflammation by selective silencing of IL-23 in antigen-presenting cells. Proc Natl Acad Sci U S A 112: 2163–2168. DOI: 10.1073/pnas.1416922112

Said A, Bock S, Müller G, Weindl G (2015) Inflammatory conditions distinctively alter immunological functions of Langerhans-like cells and dendritic cells in vitro. Immunology 144: 218-230. DOI: 10.1111/imm.12363

Said A, Bock S, Lajqi T, Müller G, Weindl G (2014) Chloroquine Promotes IL-17 Production by CD4+ T Cells via p38-Dependent IL-23 Release by Monocyte-Derived Langerhans-like Cells. J Immunol 193: 6135-6143. DOI: 10.4049/jimmunol.1303276

Kumar S, Alnasif N, Fleige E, Kurniasih I, Kral V, Haase A, Luch A, Weindl G, Haag R, Schäfer-Korting M, Hedtrich S (2014) Impact of structural differences in hyperbranched polyglycerol-polyethylene glycol nanoparticles on dermal drug delivery and biocompatibility. Eur J Pharm Biopharm 88: 625-634. DOI: 10.1016/j.ejpb.2014.10.014

Do N, Weindl G, Fleige E, Salwiczek M, Koksch B, Haag R, Schäfer-Korting M (2014) Core-multishell nanotransporters enhance skin penetration of the cell-penetrating peptide low molecular weight protamine. Polymer Adv Tech 25: 1337-1341. DOI: 10.1002/pat.3362

Do N, Weindl G, Grohmann L, Salwiczek M, Koksch B, Korting HC, Schäfer-Korting M (2014) Cationic membrane-active peptides - anticancer and antifungal activity as well as penetration into human skin. Exp Dermatol 23: 326-331. DOI: 10.1111/exd.12384

Eckl KM, Weindl G, Ackermann K, Küchler S, Casper R, Radowski M, Haag R, Hennies HC, Schäfer-Korting M (2014) Increased cutaneous absorption reflects impaired barrier function of reconstructed skin models mimicking keratinisation disorders. Exp Dermatol 23: 286-288. DOI: 10.1111/exd.12366

Ali-von Laue C, Zoschke C, Do N, Lehnen D, Küchler S, Mehnert W, Blaschke T, Kramer KD, Plendl J, Weindl G, Korting HC, Hoeller Obrigkeit D, Merk HF, Schäfer-Korting M (2014) Improving topical non-melanoma skin cancer treatment: In vitro efficacy of a novel guanosine-analog phosphonate. Skin Pharmacol Physiol 27: 173-180. DOI: 10.1159/000354118

Hamidi S, Schäfer-Korting M, Weindl G (2014) TLR2/1 and sphingosine 1-phosphate modulate inflammation, myofibroblast differentiation and cell migration in fibroblasts. Biochim Biophys Acta 1841: 484-494. DOI: 10.1016/j.bbalip.2014.01.008

Bätz FM, Klipper W, Korting HC, Henkler F, Landsiedel R, Luch A, von Fritschen U, Weindl G, Schäfer-Korting M (2013) Esterase activity in excised and reconstructed human skin - Biotransformation of prednicarbate and the model dye fluorescein diacetate. Eur J Pharm Biopharm 84: 374-85. DOI: 10.1016/j.ejpb.2012.11.008

Wagener J, Weindl G, de Groot PW, de Boer AD, Kaesler S, Thavaraj S, Bader O, Mailänder-Sanchez D, Borelli C, Weig M, Biedermann T, Naglik JR, Korting HC, Schaller M (2012) Glycosylation of Candida albicans cell wall proteins is critical for induction of innate immune responses and apoptosis of epithelial cells. PLoS One 7: e50518. DOI: 10.1371/journal.pone.0050518

Weindl G, Castello F, Schäfer-Korting M (2011) Evaluation of anti-inflammatory and atrophogenic effects of glucocorticoids on reconstructed human skin. Altern Lab Anim 39: 173-187. Full text

de Boer AD, de Groot PW, Weindl G, Schaller M, Riedel D, Diez-Orejas R, Klis FM, de Koster CG, Dekker HL, Gross U, Bader O, Weig M (2010) The Candida albicans cell wall protein Rhd3/Pga29 is abundant in the yeast form and contributes to virulence. Yeast 27: 611-624. DOI: 10.1002/yea.1790

Küchler S, Wolf NB, Heilmann S, Weindl G, Helfmann J, Yahya MM, Stein C, Schäfer-Korting M (2010) 3D-wound healing model: influence of morphine and solid lipid nanoparticles. J Biotechnol 148: 24-30. DOI: 10.1016/j.jbiotec.2010.01.001

Schaller M, Borelli C, Berger U, Walker B, Schmidt S, Weindl G, Jäckel A (2009) Susceptibility testing of amorolfine, bifonazole and ciclopiroxolamine against Trichophyton rubrum in an in vitro model of dermatophyte nail infection. Med Mycol 47: 753-758. DOI: 10.3109/13693780802577892

Wolf NB, Küchler S, Radowski MR, Blaschke T, Kramer KD, Weindl G, Kleuser B, Haag R, Schäfer-Korting M (2009) Influences of opioids and nanoparticles on in vitro wound healing models. Eur J Pharm Biopharm 73: 34-42. DOI: 10.1016/j.ejpb.2009.03.009

Naglik JR, Moyes D, Makwana J, Kanzaria P, Tsichlaki E, Weindl G, Tappuni AR, Rodgers CA, Woodman AJ, Challacombe SJ, Schaller M, Hube B (2008) Quantitative expression of the Candida albicans secreted aspartyl proteinase gene family in human oral and vaginal candidiasis. Microbiology 154: 3266-3280. DOI: 10.1099/mic.0.2008/022293-0

Weindl G, Naglik JR, Kaesler S, Biedermann T, Hube B, Korting HC, Schaller M (2007) Human Epithelial Cells Establish Direct Antifungal Defense through TLR4-Mediated Signaling. J Clin Invest 117: 3664-3672. DOI: 10.1172/JCI28115

Rebholz B, Haase I, Eckelt B, Paxian S, Flaig MJ, Ghoreschi K, Nedospasov SA, Mailhammer R, Debey-Pascher S, Schultze JL, Weindl G, Förster I, Huss R, Stratis A, Ruzicka T, Röcken M, Pfeffer K, Schmid RM, Rupec RA (2007) Crosstalk between Keratinocytes and Adaptive Immune Cells in an IkappaBalpha-Mediated Inflammatory Disease of the Skin. Immunity 27: 296-307. DOI: 10.1016/j.immuni.2007.05.024

Fradin C, Mavor AL, Weindl G, Schaller M, Hanke K, Kaufmann SHE, Mollenkopf H, Hube B (2007) The early transcriptional response of human granulocytes to infection with Candida albicans is not essential for killing but reflects cellular communications. Infect Immun 75: 1493-1501. DOI: 10.1128/IAI.01651-06

Schaller M, Zakikhany K, Naglik JR, Weindl G, Hube B (2006) Models of oral and vaginal candidiasis based on in vitro reconstituted human epithelia. Nat Protoc 1: 2767-2773. DOI: 10.1038/nprot.2006.474

Borelli C, Merk K, Schaller M, Jacob K, Vogeser M, Weindl G, Berger U, Plewig G (2006) In vivo Porphyrin Production by P. acnes in Untreated Acne Patients and its Modulation by Acne Treatment. Acta Derm Venereol 86: 316-319. DOI: 10.2340/00015555-0088

Rupec RA, Jundt F, Rebholz B, Eckelt B, Weindl G, Herzinger T, Flaig M, Moosmann S, Plewig G, Dörken B, Förster I, Huss R, Pfeffer K (2005) Stroma-Mediated Dysregulation of Liver and Bone Marrow Myelopoiesis in Mice Lacking IkappaB-alpha. Immunity 22: 479-491. DOI: 10.1016/j.immuni.2005.02.009

Roeder A, Kirschning CJ, Schaller M, Weindl G, Wagner H, Korting HC, Rupec RA (2004) Induction of nuclear factor-kappa B and c-Jun/activator protein-1 via toll-like receptor 2 in macrophages by antimycotic-treated Candida albicans. J Infect Dis 190: 1318-1326. DOI: 10.1086/423854