Takudrei

028
Synthesis and characterization of a unimolecular capsule

M. S. Brody, C. A. Schalley, D. M. Rudkevich, J. Rebek, Jr.— 1999

There is more than one way to assemble the two halves of a tethered, urea-substituted calix[4]arene dimer (shown schematically): formation of unimolecular capsules (far left), dimers, or oligomers. By combination of NMR spectroscopy and electrospray mass spectrometry, a hexamethylene spacer was shown to be exactly right to permit the preferential formation of a unimolecular capsule under inclusion of solvent or other guest molecules.

Title028
Synthesis and characterization of a unimolecular capsule
AuthorM. S. Brody, C. A. Schalley, D. M. Rudkevich, J. Rebek, Jr.
Date19990601
IdentifierDOI 10.1002/(SICI)1521-3773(19990601)38:11<1640::AID-ANIE1640>3.0.CO;2-Y; 10.1002/(SICI)1521-3757(19990601)111:11<1738::AID-ANGE1738>3.0.CO;2-5
Source(s)
CitationAngew. Chem. Int. Ed. 1999, 38, 1640-1644; Angew. Chem. 1999, 111, 1738-1742
TypeText