Takudrei

193
Supramolecular reactivity in the gas phase: Investigating the intrinsic properties of non-covalent complexes

L. Cera, C. A. Schalley— 2014

The high vacuum inside a mass spectrometer offers unique conditions to broaden our view on the reactivity of supramolecules. Because dynamic exchange processes between complexes are efficiently suppressed, the intrinsic and intramolecular reactivity of the complexes of interest is observed. Besides this, the significantly higher strength of non-covalent interactions in the absence of competing solvent allows processes to occur that are unable to compete in solution. The present review highlights a series of examples illustrating different aspects of supramolec-ular gas-phase reactivity ranging from the dissociation and formation of covalent bonds in non-covalent complexes through the reactivity in the restricted inner phase of container molecules and step-by-step mechanistic studies of organocatalytic reaction cycles to cage contraction reactions, processes induced by electron capture, and finally dynamic molecular motion within non-covalent complexes as unravelled by hydrogen-deuterium exchange processes performed in the gas phase.

Title193
Supramolecular reactivity in the gas phase: Investigating the intrinsic properties of non-covalent complexes
AuthorL. Cera, C. A. Schalley
Date20140117
IdentifierDOI 10.1039/C3CS60360A
Source(s)
CitationChem. Soc. Rev. 2014, 43, 1800-1812