An Overview of N-Heterocyclic Carbenes

M. N. Hopkinson, C. Richter, M. Schedler, F. Glorius*— 2014

The successful isolation and characterization of an N-heterocyclic carbene in 1991 opened up a new class of organic compounds for investigation. From these beginnings as academic curiosities, N-heterocyclic carbenes today rank among the most powerful tools in organic chemistry, with numerous applications in commercially important processes. Here we provide a concise overview of N-heterocyclic carbenes in modern chemistry, summarizing their general properties and uses and highlighting how these features are being exploited in a selection of pioneering recent studies.

Title16. An Overview of N-Heterocyclic Carbenes
AuthorM. N. Hopkinson, C. Richter, M. Schedler, F. Glorius*
PublisherNature
Date2014
IdentifierDOI: 10.1038/nature13384
Source(s)
CitationNature 2014, 510, 485-496