Junior Professor Matthew Hopkinson

Matthew Hopkinson

Field of Activity

Organofluorine Chemistry

Address Takustr. 3
Room 21.04
14195 Berlin
Telephone +49 30 83861438
Fax +49 30 838461438
Email matthew.hopkinson@fu-berlin.de
19.11.1984 Born in Aylesbury (UK) 

Higher Education

2007 – 2011

DPhil in Organic Chemistry, Merton College, University of Oxford (UK), Supervisor: Prof. Véronique Gouverneur

DPhil Thesis Title: “Transition Metal Catalysis in the Presence of Fluorinating Reagents”

2003 – 2007

MChem in Chemistry, Pembroke College, University of Oxford (UK), Masters Project Supervisor: Prof. Véronique Gouverneur

Masters Thesis Title: “The Electrophilic Fluorination of Hetero-Diels-Alder Adducts”

Academic Career

Aug 2016 – Present Junior Professor (W1), Freie Universität Berlin (Germany)
Jan 2012 – May 2016 Post-Doctoral Research / Alexander von Humboldt Fellowship, Westfälische Wilhelms-Universität Münster (Germany), Supervisor: Prof. Dr. Frank Glorius
July – Oct 2011 Post-Doctoral Research, University of Oxford (UK), Supervisor: Prof. Véronique Gouverneur

Awards and Fellowships

2012-2014 Postdoctoral Fellowship from the Alexander von Humboldt Foundation
2011 Simms Fund Bursary from Merton College, Oxford
2008 Commendation for outstanding PRS Transfer Report by Eli Lilly and Company
2007-2011 GlaxoSmithKline CASE Award PhD Fellowship
2007 GlaxoSmithKline Award for Organic Chemistry Part II, 2006/7


             

          

                                    

                    

The incorporation of fluorine or fluorine-containing groups into organic molecules can have a dramatic impact on their chemical and biological properties. In particular, fluorinated pharmaceuticals often exhibit improved potency compared to their non-fluorinated analogues and are more metabolically stable. The comparative lack of fluorine-containing natural products means that access to these compounds relies heavily on synthetic organic chemistry and new methods that offer improved efficiency and selectivity or even allow for the preparation of unprecendented classes of organofluorine compound are highly desired.

Our research is centred on the design and application of new methodologies for the synthesis of fluorine-containing organic molecules relevant as pharmaceuticals and agrochemicals. We are particularly interested in the development of catalytic strategies for the incorporation of fluorine or fluorine-containing functional groups such as the CF3, SCF3 and SF5 moiety, focusing principally, but not exclusively, on photocatalytic methods that harness energy from abundant and sustainable visible light. Within these projects we also endeavour to introduce new general catalysis concepts that could prove beneficial in many areas of organic synthesis beyond fluorine chemistry.

This work is conducted as part of the DFG-Research Training Network "Fluorine as a Key Element" (GRK 1582).