4. Vinylogous Mukaiyama Aldol Reactions with Triarylboranes

M. Christmann, M. Kalesse

The first vinylogous Mukaiyama aldol reactions with tris(pentafluorophenyl)borane and triphenylborane are described. Both Lewis acids diastereoselectively generate the C19–C21 all-syn stereo triad of ratjadone, and in the case of tris(pentafluorophenyl)borane the reaction proceeds with substoichiometric amounts.

Title4. Vinylogous Mukaiyama Aldol Reactions with Triarylboranes
AuthorM. Christmann, M. Kalesse
IdentifierDOI: 10.1016/S0040-4039(00)02254-1
Source(s)
CitationTetrahedron Lett. 2001, 42, 1269-1271