38. One-Pot Oxidation/Isomerization of Z-Allylic Alcohols with Oxygen as Stoichiometric Oxidant

D. Könning, W. Hiller, M. Christmann

A method for generating (E)-α,β-unsaturated aldehydes from Z-allylic alcohols or E/Z-mixtures is described. The one-pot procedure involves a Cu-catalyzed oxidation followed by an organocatalytic Z/E-isomerization with N,N-dimethylaminopyridine (DMAP).

Title38. One-Pot Oxidation/Isomerization of Z-Allylic Alcohols with Oxygen as Stoichiometric Oxidant
AuthorD. Könning, W. Hiller, M. Christmann
IdentifierDOI: 10.1021/ol302420k
Source(s)
CitationOrg. Lett. 2012, 14, 5258-5261