11. New Developments in the Asymmetric Stetter Reaction

M. Christmann

Highly active carbene catalysts have revitalized the interest in the asymmetric Stetter reaction as a method for the construction of 1,4-dicarbonyl compounds. With the latest generation of a catalyst developed by Rovis and co-workers (1, for example), products with quaternary stereocenters such as 2 can be generated in 85 % yield and 99 % ee.

Title11. New Developments in the Asymmetric Stetter Reaction
AuthorM. Christmann
IdentifierDOI: 10.1002/anie.200500761
Source(s)
CitationAngew. Chem. Int. Ed. 2005, 44, 2632-2634