1. Synthesis of the C14-C24-Fragment of Ratjadone

M. Christmann, M. Kalesse

Ratjadone is an antifungal and highly cytotoxic polyketide from Sorangium cellulosum. The tetrahydropyran ring is supposed to result from an intramolecular opening of a C16–C17 epoxide. Herein we report the biomimetic synthesis of the C15–C24 segment of ratjadone.

Title1. Synthesis of the C14-C24-Fragment of Ratjadone
AuthorM. Christmann, M. Kalesse
IdentifierDOI: 10.1016/S0040-4039(99)01486-0
Source(s)
CitationTetrahedron Lett. 1999, 40, 7201-7204