Calderón Group

Welcome to the research group website of Prof. Dr. Marcelo Calderón!

The research interest of our group deals with the development of novel polymer therapeutic concepts. We use responsive dendritic systems and nanogels as smart polymeric systems for the improvement of the therapeutic index of drugs. Our main areas of research are: (1) multifunctional polymer-drug conjugates, (2) self-assembling amphiphiles for the controlled delivery of bioactives, (3) new diagnostic technologies as theranostic approaches, and (4) environment-responsive nanogels.

Our work is mainly focused on polymer and organic chemistry that is supported by our strong international collaboration network involving biochemists, biologists, medical doctors, etc. with knowledge in areas as gene therapy, cancer therapeutics, topical applications, amongst others.

Group picture 2016 JPEG
Calderón Group

Latest News


Our results from the collaboration with the Universidade de Santiago de Compostela, Spain, were just published by Angewandte Chemie. We demonstrated that when the elastin basic amino acid sequence VPGVG is used as a pendant group of a poly(phenylacetylene) (PPA) its thermoresponsive behavior in water can be remotely detected through conformational changes on the formed helix. Congratulations to Julian and the collaboration partners!